SCHEMBL9433347

SCHEMBL9433347

CCCCCC1=CCCO1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 4/20 0.32
CYP3A4 P08684 2/20 0.32
SCD O00767 1/20 0.32
CHRM2 P08172 3/20 0.31
CHRM5 P08912 3/20 0.31
CHRM1 P11229 3/20 0.31
CHRM3 P20309 3/20 0.31
ESR1 P03372 2/20 0.31
ADRA2A P08913 2/20 0.31
ADORA3 P0DMS8 2/20 0.31
TACR2 P21452 2/20 0.31
SLC6A2 P23975 2/20 0.31
SLC6A4 P31645 2/20 0.31
SLC6A3 Q01959 2/20 0.31
KCNH2 Q12809 2/20 0.31
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
SHBG P04278 1/20 0.31
TP53 P04637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28309887 0.98 SCD (0.35) PTGS2CYP3A4SCDCHRM2CHRM5
SCHEMBL5502964 0.98 SCD (0.35) PTGS2CYP3A4SCDCHRM2CHRM5
SCHEMBL32665724 0.98 SCD (0.35) PTGS2CYP3A4SCDCHRM2CHRM5
SCHEMBL28159466 0.98 SCD (0.35) PTGS2CYP3A4SCDCHRM2CHRM5
SCHEMBL2160075 0.98 SCD (0.35) PTGS2CYP3A4SCDCHRM2CHRM5
SCHEMBL18076301 0.98 SCD (0.35) PTGS2CYP3A4SCDCHRM2CHRM5
SCHEMBL13666857 0.94
SCHEMBL13950243 0.85
SCHEMBL7782028 0.82
SCHEMBL5975166 0.72 ACHE (0.42) PTGS2KCNH2ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200138232-A1 DISPOSABLE BEVERAGE POD AND APPARATUS FOR MAKING A BEVERAGE ALTRIA CLIENT SERVICES LLC (US) 2020-05-07 US disclosed
CN-108778349-A Spice composition 奇华顿股份有限公司 2018-11-09 CN disclosed
CN-108348629-A Perfume composition and air freshener device 奇华顿股份有限公司 2018-07-31 CN disclosed
US-9771552-B2 Flavor system and method for making sherry wine like beverages ALTRIA CLIENT SERVICES LLC (US) 2017-09-26 US disclosed
US-20170202250-A1 FLAVOR SYSTEM AND METHOD FOR MAKING BEVERAGES ALTRIA CLIENT SERVICES LLC 2017-07-20 US disclosed
WO-2016100606-A1 SILYLATION OF AROMATIC HETEROCYCLES BY DISILANES USING POTASSIUM ALKOXIDE CATALYSTS CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2016-06-23 WO disclosed
US-20150259634-A1 FLAVOR SYSTEM AND METHOD FOR MAKING SHERRY WINE LIKE BEVERAGES Altria Client Services Inc. (US) 2015-09-17 US disclosed
US-5340833-A Antiarthritic, antiinflammatory, antitumor agents EISAI CO., LTD. (JP) 1994-08-23 US disclosed
EP-0568289-A2 Benzothiophenes and thienothiophenes and related compounds useful, for example, as urokinase inhibitors Eisai Co., Ltd. (JP) 1993-11-03 EP disclosed