Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.58 |
| ▸ | CASP1 | P29466 | 3/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.44 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.44 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9434813 | 0.88 | KDM4E (0.41) | KDM4EHSD17B10CASP1CASP7ALDH1A1 | |
| SCHEMBL9434085 | 0.86 | KDM4E (0.61) | KDM4EHSD17B10CASP1CASP7ALDH1A1 | |
| SCHEMBL10432455 | 0.86 | KDM4E (0.64) | KDM4EHSD17B10CASP1CASP7ALDH1A1 | |
| SCHEMBL7164235 | 0.84 | CYP2C9 (0.59) | KDM4EHSD17B10ALDH1A1HPGDGAA | |
| SCHEMBL9433590 | 0.84 | KDM4E (0.61) | KDM4EHSD17B10CASP1CASP7ALDH1A1 | |
| SCHEMBL9434428 | 0.84 | KDM4E (0.61) | KDM4EHSD17B10CASP1CASP7ALDH1A1 | |
| SCHEMBL9434613 | 0.84 | KDM4E (0.61) | KDM4EHSD17B10CASP1CASP7ALDH1A1 | |
| SCHEMBL9434114 | 0.82 | KDM4E (0.81) | KDM4EHSD17B10CASP1CASP7ALDH1A1 | |
| SCHEMBL9434276 | 0.82 | KDM4E (0.59) | KDM4EHSD17B10CASP1CASP7ALDH1A1 | |
| SCHEMBL9433816 | 0.82 | CACNA1C (0.46) | KDM4EHSD17B10CASP1CASP7ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5276150-A | Vasodilators, anticoagulants, calcium channel blockers | FUJIREBIO INC. (JP) | 1994-01-04 | — | — | US | disclosed |
| EP-0400660-A1 | 1,4-dihydropyridine derivatives | FUJIREBIO INC. (JP) | 1990-12-05 | — | — | EP | disclosed |