Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | CASP1 | P29466 | 3/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 2/20 | 0.35 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | KDM6B | O15054 | 1/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | KDM5C | P41229 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.33 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9433832 | 0.88 | KDM4E (0.58) | KDM4EHSD17B10CASP1CASP7CACNA1C | |
| SCHEMBL9433813 | 0.85 | KDM4E (0.43) | KDM4EHSD17B10CASP1CASP7CACNA1B | |
| SCHEMBL9433540 | 0.85 | KDM4E (0.45) | KDM4EHSD17B10CASP1CASP7CACNA1B | |
| SCHEMBL9433568 | 0.84 | KDM4E (0.44) | KDM4EHSD17B10CASP1CASP7CACNA1B | |
| SCHEMBL10642720 | 0.83 | KDM4E (0.47) | KDM4EHSD17B10CASP1GSK3BCASP7 | |
| SCHEMBL9434790 | 0.83 | KDM4E (0.43) | KDM4EHSD17B10CASP1CASP7CACNA1B | |
| SCHEMBL9434846 | 0.83 | ALDH1A1 (0.43) | KDM4EHSD17B10CASP1CASP7CACNA1B | |
| SCHEMBL9433578 | 0.81 | MAPT (0.44) | KDM4EHSD17B10CASP1CACNA1CCACNA1B | |
| SCHEMBL9433749 | 0.81 | KDM4E (0.47) | KDM4EHSD17B10CASP1ALDH1A1GAA | |
| SCHEMBL9434815 | 0.81 | CACNA1C (0.44) | KDM4EHSD17B10CASP1GSK3BCASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5276150-A | Vasodilators, anticoagulants, calcium channel blockers | FUJIREBIO INC. (JP) | 1994-01-04 | — | — | US | disclosed |
| EP-0400660-A1 | 1,4-dihydropyridine derivatives | FUJIREBIO INC. (JP) | 1990-12-05 | — | — | EP | disclosed |