Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9433723 | 0.88 | KDM4E (0.63) | KDM4EHSD17B10CASP1ALDH1A1MAPT | |
| SCHEMBL9434054 | 0.84 | FFAR3 (0.41) | KDM4EHSD17B10CASP1ALDH1A1KMT2A | |
| SCHEMBL9433540 | 0.82 | KDM4E (0.45) | KDM4EHSD17B10CASP1ALDH1A1KMT2A | |
| SCHEMBL9434000 | 0.81 | CACNA1B (0.51) | KDM4EHSD17B10CASP1ALDH1A1KMT2A | |
| SCHEMBL9434752 | 0.80 | KDM4E (0.45) | KDM4EHSD17B10CASP1ALDH1A1MAPT | |
| SCHEMBL9433568 | 0.79 | KDM4E (0.44) | KDM4EHSD17B10CASP1ALDH1A1KMT2A | |
| SCHEMBL10432703 | 0.79 | KDM4E (0.44) | KDM4EHSD17B10CASP1ALDH1A1MAPT | |
| SCHEMBL9434410 | 0.78 | CACNA1B (0.45) | KDM4EHSD17B10CASP1ALDH1A1MAPT | |
| SCHEMBL9433915 | 0.78 | KDM4E (0.46) | KDM4EHSD17B10CASP1ALDH1A1MAPT | |
| SCHEMBL9433813 | 0.78 | KDM4E (0.43) | KDM4EHSD17B10CASP1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5276150-A | Vasodilators, anticoagulants, calcium channel blockers | FUJIREBIO INC. (JP) | 1994-01-04 | — | — | US | disclosed |
| EP-0400660-A1 | 1,4-dihydropyridine derivatives | FUJIREBIO INC. (JP) | 1990-12-05 | — | — | EP | disclosed |