Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 2/20 | 0.34 |
| ▸ | RARA | P10276 | 1/20 | 0.34 |
| ▸ | RARG | P13631 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 4/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9472502 | 0.91 | ACACB (0.38) | RARBRARARARGHSD17B10TSHR | |
| SCHEMBL8755593 | 0.88 | FFAR1 (0.37) | RARBRARARARGHSD17B10FFAR1 | |
| SCHEMBL8766258 | 0.88 | CYP17A1 (0.37) | RARBRARARARGHSD17B10TSHR | |
| SCHEMBL28960111 | 0.88 | RARB (0.41) | RARBRARARARGHSD17B10TSHR | |
| SCHEMBL9473097 | 0.86 | ACACB (0.40) | FFAR1ACACBFFAR4GAA | |
| SCHEMBL28900110 | 0.85 | RARB (0.38) | RARBRARARARGHSD17B10FFAR1 | |
| SCHEMBL9434250 | 0.84 | MCHR1 (0.40) | RARBRARAHSD17B10HTR2AMCHR1 | |
| SCHEMBL9433719 | 0.83 | SMN1; SMN2 (0.48) | HSD17B10NPC1TP53PKMRAB9A | |
| SCHEMBL9433010 | 0.83 | NPC1 (0.34) | RARBHSD17B10NPC1TP53PKM | |
| SCHEMBL25548582 | 0.83 | FFAR1 (0.42) | RARBRARARARGHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5372746-A | Fluoro-substituted tolane compounds and liquid crystalline mixtures containing same | HOFFMANN-LA ROCHE INC. (US) | 1994-12-13 | — | — | US | disclosed |