Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLO1 | Q04760 | 2/20 | 0.61 |
| ▸ | TGM2 | P21980 | 1/20 | 0.51 |
| ▸ | FBP1 | P09467 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 8/20 | 0.48 |
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | XBP1 | P17861 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.48 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.48 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.48 |
| ▸ | RAB27A | P51159 | 1/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9434390 | 1.00 | GLO1 (0.61) | GLO1TGM2FBP1MAPTLMNA | |
| SCHEMBL9434342 | 0.86 | GLO1 (0.63) | GLO1TGM2FBP1MAPTLMNA | |
| SCHEMBL9434339 | 0.86 | GLO1 (0.63) | GLO1TGM2FBP1MAPTLMNA | |
| SCHEMBL9433982 | 0.80 | SMN1; SMN2 (0.61) | GLO1TGM2FBP1MAPTLMNA | |
| SCHEMBL9433972 | 0.80 | SMN1; SMN2 (0.61) | GLO1TGM2FBP1MAPTLMNA | |
| SCHEMBL9433701 | 0.80 | GLO1 (0.64) | GLO1FBP1MAPTLMNASMN1; SMN2 | |
| SCHEMBL9433707 | 0.80 | GLO1 (0.64) | GLO1FBP1MAPTLMNASMN1; SMN2 | |
| SCHEMBL9434178 | 0.79 | GLO1 (0.54) | GLO1FBP1MAPTLMNANPC1 | |
| SCHEMBL9434172 | 0.79 | GLO1 (0.54) | GLO1FBP1MAPTLMNANPC1 | |
| SCHEMBL8028846 | 0.77 | GLO1 (1.00) | GLO1FBP1MAPTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5276150-A | Vasodilators, anticoagulants, calcium channel blockers | FUJIREBIO INC. (JP) | 1994-01-04 | — | — | US | disclosed |
| EP-0400660-A1 | 1,4-dihydropyridine derivatives | FUJIREBIO INC. (JP) | 1990-12-05 | — | — | EP | disclosed |