Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 14/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9433666 | 0.90 | CACNA1B (0.50) | CACNA1BKDM4EHSD17B10CASP1 | |
| SCHEMBL9434101 | 0.89 | CACNA1B (0.46) | CACNA1BKDM4EHSD17B10CASP1 | |
| SCHEMBL9433819 | 0.88 | CACNA1B (0.52) | CACNA1BKDM4EHSD17B10CASP1 | |
| SCHEMBL9434633 | 0.88 | CACNA1B (0.59) | CACNA1B | |
| SCHEMBL9434036 | 0.88 | CACNA1B (0.52) | CACNA1BKDM4EHSD17B10CASP1 | |
| SCHEMBL10432703 | 0.87 | KDM4E (0.44) | CACNA1BTP53KDM4EHSD17B10CASP1 | |
| SCHEMBL9433379 | 0.86 | KDM4E (0.46) | CACNA1BTP53KDM4EHSD17B10CASP1 | |
| SCHEMBL9434076 | 0.85 | CACNA1F (0.46) | CACNA1BKDM4EHSD17B10CASP1 | |
| SCHEMBL9433733 | 0.84 | CACNA1B (0.55) | CACNA1BMEN1KMT2A | |
| SCHEMBL9434752 | 0.83 | KDM4E (0.45) | CACNA1BKDM4EHSD17B10CASP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5276150-A | Vasodilators, anticoagulants, calcium channel blockers | FUJIREBIO INC. (JP) | 1994-01-04 | — | — | US | disclosed |
| EP-0400660-A1 | 1,4-dihydropyridine derivatives | FUJIREBIO INC. (JP) | 1990-12-05 | — | — | EP | disclosed |