⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9132578 | 0.87 | PAOX (0.46) | — | |
| SCHEMBL7702340 | 0.73 | — | — | |
| SCHEMBL68956 | 0.71 | — | — | |
| SCHEMBL921645 | 0.69 | — | — | |
| SCHEMBL28797562 | 0.69 | — | — | |
| SCHEMBL14827797 | 0.69 | — | — | |
| SCHEMBL219402 | 0.69 | — | — | |
| SCHEMBL18379007 | 0.69 | — | — | |
| SCHEMBL18950210 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL1128658 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2061799-A2 | METHODS AND COMPOSITIONS FOR THE USE OF LYSINE RIBOSWITCHES | YALE UNIVERSITY (US) | 2009-05-27 | — | — | EP | claimed |
| WO-2008033866-A2 | METHODS AND COMPOSITIONS FOR THE USE OF LYSINE RIBOSWITCHES | YALE UNIVERSITY (US) | 2008-03-20 | — | — | WO | claimed |
| EP-2426219-A1 | Riboswitches and methods and compositions for use of and with riboswitches | Yale University (US) | 2012-03-07 | — | — | EP | disclosed |
| EP-2426218-A1 | Riboswitches and methods and compositions for use of and with riboswitches | Yale University (US) | 2012-03-07 | — | — | EP | disclosed |
| EP-2139909-A1 | PREQ1 RIBOSWITCHES AND METHODS AND COMPOSITIONS FOR USE OF AND WITH PREQ1 RIBOSWITCHES | Yale University, Inc. (US) | 2010-01-06 | — | — | EP | disclosed |
| EP-2061799-A2 | METHODS AND COMPOSITIONS FOR THE USE OF LYSINE RIBOSWITCHES | YALE UNIVERSITY (US) | 2009-05-27 | — | — | EP | disclosed |
| WO-2008116223-A1 | PREQ1 RIBOSWITCHES AND METHODS AND COMPOSITIONS FOR USE OF AND WITH PREQ1 RIBOSWITCHES | YALE UNIVERSITY (US) | 2008-09-25 | — | — | WO | disclosed |
| WO-2008033866-A2 | METHODS AND COMPOSITIONS FOR THE USE OF LYSINE RIBOSWITCHES | YALE UNIVERSITY (US) | 2008-03-20 | — | — | WO | disclosed |