⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3371380 | 0.90 | — | — | |
| SCHEMBL9132578 | 0.79 | PAOX (0.46) | — | |
| SCHEMBL2333897 | 0.77 | — | — | |
| SCHEMBL2933239 | 0.76 | — | — | |
| SCHEMBL3287225 | 0.76 | ALDH1A1 (0.33) | — | |
| SCHEMBL94345 | 0.73 | — | — | |
| SCHEMBL28797562 | 0.73 | — | — | |
| SCHEMBL14827797 | 0.73 | — | — | |
| SCHEMBL219402 | 0.73 | — | — | |
| SCHEMBL18379007 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106977577-A | The synthesis of two class abiraterone derivatives | 湖南师范大学 | 2017-07-25 | — | — | CN | claimed |
| EP-0272562-B1 | Basic adhesive polymeric mass transmitting the active ingredient, method for making it and its use | LOHMANN THERAPIE SYST LTS (DE) | 1994-03-09 | — | — | EP | claimed |
| US-11629266-B2 | Waterborne composition | DOW GLOBAL TECHNOLOGIES LLC (US) | 2023-04-18 | — | — | US | disclosed |
| CN-112771112-B | Aqueous composition | 陶氏环球技术有限责任公司 | 2023-03-21 | — | — | CN | disclosed |
| EP-3864086-A1 | WATERBORNE COMPOSITION | Dow Global Technologies LLC (US) | 2021-08-18 | — | — | EP | disclosed |
| US-20210238423-A1 | WATERBORNE COMPOSITION | ROHM AND HAAS COMPANY | 2021-08-05 | — | — | US | disclosed |
| CN-112771112-A | Aqueous composition | 陶氏环球技术有限责任公司 | 2021-05-07 | — | — | CN | disclosed |
| CN-108472284-A | β -lactamase inhibitor | 维纳拓尔斯制药公司 | 2018-08-31 | — | — | CN | disclosed |
| CN-107922394-A | 3 tetrazole radical benzene, 1,2 disulfonic acid amide derivative as metal beta lactamase restrainer | 默沙东公司 | 2018-04-17 | — | — | CN | disclosed |
| CN-107921145-A | The antibody drug conjugate of KSP inhibitor and anti-TWEAKR antibody（ADC） | 拜耳医药股份有限公司 | 2018-04-17 | — | — | CN | disclosed |
| CN-104837503-A | Compounds and methods for inhibiting NHE-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal disorders | ARDELYX INC | 2015-08-12 | — | — | CN | disclosed |
| CN-1882347-A | AKT protein kinase inhibitors | ARRAY BIOPHARMA INC (US) | 2006-12-20 | — | — | CN | disclosed |
| CN-1829709-A | Bicyclic imidazol derivatives against flaviviridae | GENELABS TECH INC (US) | 2006-09-06 | — | — | CN | disclosed |
| CN-1568187-A | 2H-2,3-dinitrogen phenodiazine-1-ketone and using method thereof | ICOS CORP (US) | 2005-01-19 | — | — | CN | disclosed |
| EP-1226167-A1 | MODIFIED PEPTIDES AND PEPTIDOMIMETICS FOR USE IN IMMUNOTHERAPY | Akzo Nobel N.V. (NL) | 2002-07-31 | — | — | EP | disclosed |
| WO-2001029081-A1 | MODIFIED PEPTIDES AND PEPTIDOMIMETICS FOR USE IN IMMUNOTHERAPY | AKZO NOBEL N.V. (NL) | 2001-04-26 | — | — | WO | disclosed |
| CN-1170405-A | Aryl and heteroaryl sulfonamide derivatives, their preparation and their use as endothelin antagonists | HOFFMANN LA ROCHE (CH) | 1998-01-14 | — | — | CN | disclosed |
| CN-1023479-C | Process for preparing monoamide derivatives of ethylenediamine | HOFFMANN LA ROCHE (CH) | 1994-01-12 | — | — | CN | disclosed |
| EP-0562832-A1 | Indole and indazole derivatives, for the treatment and prophylaxis of cerebral disorders, their preparation and their use | SANKYO COMPANY LIMITED (JP) | 1993-09-29 | — | — | EP | disclosed |
| CN-85107182-A | Process for preparing monoamide derivatives of ethylenediamine | — | 1987-04-08 | — | — | CN | disclosed |