Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 11/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.70 |
| ▸ | TP53 | P04637 | 1/20 | 0.70 |
| ▸ | HTT | P42858 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 6/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.65 |
| ▸ | MAPT | P10636 | 4/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | GAA | P10253 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | THRB | P10828 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9434834 | 0.90 | L3MBTL1 (0.67) | L3MBTL1MAPK1TP53HTTKMT2A | |
| SCHEMBL11782499 | 0.88 | L3MBTL1 (0.72) | L3MBTL1MAPK1TP53HTTKMT2A | |
| SCHEMBL21392893 | 0.88 | L3MBTL1 (0.71) | L3MBTL1MAPK1TP53HTTKMT2A | |
| SCHEMBL7924804 | 0.86 | L3MBTL1 (0.70) | L3MBTL1MAPK1TP53HTTKMT2A | |
| SCHEMBL8787198 | 0.85 | L3MBTL1 (0.64) | L3MBTL1MAPK1TP53HTTKMT2A | |
| SCHEMBL15911145 | 0.83 | L3MBTL1 (0.63) | L3MBTL1MAPK1TP53HTTKMT2A | |
| SCHEMBL7720888 | 0.83 | L3MBTL1 (0.74) | L3MBTL1KMT2AMEN1POLBLMNA | |
| SCHEMBL11045465 | 0.82 | L3MBTL1 (0.62) | L3MBTL1MAPK1TP53HTTKMT2A | |
| SCHEMBL3518000 | 0.82 | KMT2A (0.66) | L3MBTL1MAPK1TP53HTTKMT2A | |
| SCHEMBL14192656 | 0.81 | KMT2A (0.82) | KMT2AMEN1POLBCYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5324722-A | Analgesics | G. D. SEARLE & CO. (US) | 1994-06-28 | — | — | US | disclosed |
| WO-1993013082-A1 | SUBSTITUTED DIBENZOXAZEPINES OR DIBENZOTHIAZEPINES AND THEIR USE AS PROSTAGLANDIN E2 ANTAGONISTS | G.D. SEARLE & CO. (US) | 1993-07-08 | — | — | WO | disclosed |