Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIMK1 | P53667 | 4/20 | 0.66 |
| ▸ | IKBKB | O14920 | 2/20 | 0.66 |
| ▸ | OGG1 | O15527 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11074064 | 0.79 | LIMK1 (0.68) | LIMK1IKBKBOGG1MCL1KDM4E | |
| SCHEMBL6609258 | 0.79 | LIMK1 (1.00) | LIMK1IKBKBOGG1MCL1KDM4E | |
| SCHEMBL649968 | 0.79 | LIMK1 (0.68) | LIMK1IKBKBOGG1MCL1KDM4E | |
| Hydrochloric Acid SCHEMBL11077705 | 0.78 | LIMK1 (0.66) | LIMK1IKBKBOGG1MCL1KDM4E | |
| SCHEMBL7675240 | 0.78 | MCL1 (0.71) | LIMK1IKBKBOGG1MCL1KDM4E | |
| SCHEMBL2702750 | 0.78 | LIMK1 (0.68) | LIMK1IKBKBOGG1MCL1KDM4E | |
| SCHEMBL347996 | 0.78 | LIMK1 (0.66) | LIMK1IKBKBOGG1MCL1KDM4E | |
| SCHEMBL29483598 | 0.78 | LIMK1 (0.68) | LIMK1IKBKBOGG1MCL1KDM4E | |
| SCHEMBL13969608 | 0.74 | LIMK1 (1.00) | LIMK1IKBKBOGG1MCL1KDM4E | |
| SCHEMBL29483653 | 0.74 | LIMK1 (0.60) | LIMK1IKBKBOGG1MCL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5350748-A | 3-thio or amino substituted-benzo[b]thiophene-2-carboxamides and 3-oxygen, thio, or amino substituted-benzofuran-2-carboxamides as inhibitors of cell adhesion | WARNER-LAMBERT COMPANY (US) | 1994-09-27 | — | — | US | disclosed |