Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIMK1 | P53667 | 3/20 | 0.66 |
| ▸ | IKBKB | O14920 | 1/20 | 0.66 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | OGG1 | O15527 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16599338 | 0.85 | PTGS2 (0.59) | LIMK1IKBKBPTGS2HDAC1HDAC8 | |
| SCHEMBL346530 | 0.83 | MCL1 (0.62) | LIMK1IKBKBPTGS2HDAC1HDAC8 | |
| SCHEMBL30980091 | 0.81 | PTGS2 (0.56) | LIMK1IKBKBPTGS2HDAC1HDAC8 | |
| SCHEMBL2503631 | 0.81 | PTGS2 (0.56) | LIMK1IKBKBPTGS2HDAC1HDAC8 | |
| SCHEMBL6609258 | 0.79 | LIMK1 (1.00) | LIMK1IKBKBHDAC1HDAC8HDAC6 | |
| SCHEMBL649968 | 0.79 | LIMK1 (0.68) | LIMK1IKBKBMCL1KDM4EALDH1A1 | |
| SCHEMBL11074064 | 0.79 | LIMK1 (0.68) | LIMK1IKBKBMCL1KDM4EALDH1A1 | |
| SCHEMBL29483598 | 0.78 | LIMK1 (0.68) | LIMK1IKBKBHDAC1HDAC8HDAC6 | |
| SCHEMBL7675240 | 0.78 | MCL1 (0.71) | LIMK1IKBKBHDAC1HDAC8HDAC6 | |
| SCHEMBL9434697 | 0.78 | LIMK1 (0.66) | LIMK1IKBKBPTGS2HDAC1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019046668-A1 | AMIDE SUBSTITUTED THIAZOLES AS PROTEIN SECRETION INHIBITORS | KEZAR LIFE SCIENCES (US) | 2019-03-07 | — | — | WO | disclosed |
| EP-2578579-A1 | Benzothiophene carboxamide compounds, composition and applications thereof | National Institute of Immunology (IN) | 2013-04-10 | — | — | EP | disclosed |
| US-20120016014-A1 | BENZOTHIOPHENE CARBOXAMIDE COMPOUNDS, COMPOSITION AND APPLICATIONS THEREOF | INDIAN INSTITUTE OF SCIENCE (IN) | 2012-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120016014-A1 | BENZOTHIOPHENE CARBOXAMIDE COMPOUNDS, COMPOSITION AND APPLICATIONS THEREOF | PTGER2, PTGES2, PTGIR | LIMK1 3272/4885IKBKB 1303/4885PTGS2 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.