Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6299898 | 0.99 | CYP1A2 (0.43) | CYP1A2ALDH1A1SMN1; SMN2POLBMAPT | |
| SCHEMBL3220742 | 0.89 | GABRP (0.41) | ALDH1A1MAPTLMNAKDM4EHPGD | |
| SCHEMBL9435007 | 0.88 | CYP1A2 (0.41) | CYP1A2ALDH1A1SMN1; SMN2POLBMAPT | |
| SCHEMBL14135011 | 0.77 | PDE2A (0.33) | ALDH1A1LMNAKDM4EHPGDCASP1 | |
| SCHEMBL9597257 | 0.77 | ADORA1 (0.57) | CYP1A2ALDH1A1SMN1; SMN2POLBMAPT | |
| SCHEMBL3199658 | 0.73 | ADORA1 (0.40) | ALDH1A1SMN1; SMN2L3MBTL1GAA | |
| SCHEMBL1918476 | 0.73 | ADORA1 (0.54) | CYP1A2ALDH1A1SMN1; SMN2L3MBTL1KDM4E | |
| SCHEMBL4362864 | 0.71 | ADORA1 (0.41) | ALDH1A1SMN1; SMN2POLBL3MBTL1GAA | |
| SCHEMBL6306226 | 0.71 | MAPK1 (0.44) | ALDH1A1POLBMAPTLMNAKDM4E | |
| SCHEMBL3209801 | 0.70 | HTT (0.41) | CYP1A2ALDH1A1SMN1; SMN2LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994011369-A1 | ANTIHYPERTENSIVE 5-[(IMIDAZO[4,5-b]PYRIDIN-3-YL)METHYL]BENZOFURAN DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1994-05-26 | — | — | WO | disclosed |