Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.54 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 6/20 | 0.47 |
| ▸ | GRM5 | P41594 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | NSD2 | O96028 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | DPYD | Q12882 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4864732 | 0.86 | TNKS2 (0.51) | TNKS2CREBBPMAOBACHE | |
| SCHEMBL4864718 | 0.86 | TNKS2 (0.51) | TNKS2CREBBPMAOBACHE | |
| SCHEMBL4864711 | 0.86 | TNKS2 (0.51) | TNKS2CREBBPMAOBACHE | |
| SCHEMBL10242153 | 0.80 | GRM5 (0.58) | GRM5 | |
| SCHEMBL8532996 | 0.76 | GRM5 (0.49) | GRM5 | |
| SCHEMBL338191 | 0.76 | GRM5 (0.49) | GRM5 | |
| SCHEMBL5835621 | 0.76 | GRM5 (0.49) | GRM5 | |
| SCHEMBL5544656 | 0.76 | GRM5 (0.49) | GRM5 | |
| SCHEMBL6374631 | 0.76 | GRM5 (0.49) | GRM5 | |
| SCHEMBL4291 | 0.76 | GRM5 (0.49) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994000432-A1 | ANORECTIC EPINEPHRINE DERIVATIVES | THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1994-01-06 | — | — | WO | disclosed |