Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.55 |
| ▸ | CCR6 | P51684 | 1/20 | 0.55 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.50 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.50 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.47 |
| ▸ | FBP1 | P09467 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9434867 | 1.00 | MAPT (0.61) | MAPTLMNAGLO1RAB9ASMN1; SMN2 | |
| SCHEMBL9433460 | 0.83 | GLO1 (0.61) | MAPTLMNAGLO1RAB9ASMN1; SMN2 | |
| SCHEMBL9433464 | 0.83 | GLO1 (0.61) | MAPTLMNAGLO1RAB9ASMN1; SMN2 | |
| SCHEMBL9434532 | 0.82 | GLO1 (0.54) | MAPTLMNAGLO1RAB9ASMN1; SMN2 | |
| SCHEMBL12486398 | 0.80 | CYP1A2 (0.64) | MAPTLMNAGLO1RAB9ASMN1; SMN2 | |
| SCHEMBL12486396 | 0.80 | CYP1A2 (0.64) | MAPTLMNAGLO1RAB9ASMN1; SMN2 | |
| SCHEMBL14306018 | 0.80 | HSP90AA1 (0.79) | MAPTLMNARAB9ASMN1; SMN2HSP90AA1 | |
| SCHEMBL9434126 | 0.78 | GLO1 (0.57) | MAPTLMNAGLO1RAB9ASMN1; SMN2 | |
| SCHEMBL9434206 | 0.77 | GLO1 (0.56) | MAPTLMNAGLO1RAB9ASMN1; SMN2 | |
| SCHEMBL9433532 | 0.77 | GLO1 (0.56) | MAPTLMNAGLO1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5276150-A | Vasodilators, anticoagulants, calcium channel blockers | FUJIREBIO INC. (JP) | 1994-01-04 | — | — | US | disclosed |
| EP-0400660-A1 | 1,4-dihydropyridine derivatives | FUJIREBIO INC. (JP) | 1990-12-05 | — | — | EP | disclosed |