Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.44 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9214734 | 0.81 | KDM4E (0.47) | HSD17B10GAAMEN1HPGDKMT2A | |
| SCHEMBL9434620 | 0.78 | KCNK3 (0.49) | HSD17B10GAAMEN1KMT2AMAPT | |
| SCHEMBL7768116 | 0.75 | MAPT (0.53) | HSD17B10GAAMEN1HPGDKMT2A | |
| SCHEMBL11293759 | 0.73 | MAPT (0.56) | HSD17B10GAAMEN1HPGDKMT2A | |
| SCHEMBL11293754 | 0.73 | HSD17B10 (0.47) | HSD17B10GAAMEN1HPGDKMT2A | |
| SCHEMBL28067497 | 0.70 | SMN1; SMN2 (0.55) | GAAMEN1HPGDKMT2AMAPT | |
| SCHEMBL30703669 | 0.70 | HSD17B10 (1.00) | HSD17B10GAAMEN1HPGDKMT2A | |
| SCHEMBL12133 | 0.70 | HSD17B10 (1.00) | HSD17B10GAAMEN1HPGDKMT2A | |
| SCHEMBL2502058 | 0.69 | RAB9A (0.69) | HSD17B10GAAMEN1HPGDKMT2A | |
| SCHEMBL10934938 | 0.69 | MAPT (0.54) | HSD17B10GAAMEN1KMT2ARXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994024109-A1 | INDAZOLE DERIVATIVES AND ANTIVIRAL DRUGS THAT CONTAIN THEM | BOEHRINGER MANNHEIM GMBH (DE) | 1994-10-27 | — | — | WO | disclosed |