Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 5/20 | 0.50 |
| ▸ | F2 | P00734 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 3/20 | 0.35 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9435117 | 1.00 | SERPINE1 (0.50) | SERPINE1F2KMT2ANPC1RAB9A | |
| SCHEMBL9184625 | 0.90 | SERPINE1 (0.52) | SERPINE1KMT2AMAPTTDP1L3MBTL1 | |
| SCHEMBL9435379 | 0.90 | SERPINE1 (0.52) | SERPINE1KMT2AMAPTTDP1L3MBTL1 | |
| SCHEMBL8641837 | 0.87 | SERPINE1 (0.56) | SERPINE1KMT2ANPC1RAB9ACYP2C19 | |
| SCHEMBL8641841 | 0.87 | SERPINE1 (0.56) | SERPINE1KMT2ANPC1RAB9ACYP2C19 | |
| SCHEMBL9435603 | 0.85 | SERPINE1 (0.53) | SERPINE1KMT2ACYP2C19MAPTBLM | |
| SCHEMBL9435600 | 0.85 | SERPINE1 (0.53) | SERPINE1KMT2ACYP2C19MAPTBLM | |
| SCHEMBL9435397 | 0.85 | SERPINE1 (0.53) | SERPINE1KMT2ANPC1RAB9ACYP2C19 | |
| SCHEMBL9187618 | 0.85 | SERPINE1 (0.53) | SERPINE1KMT2ANPC1RAB9ACYP2C19 | |
| SCHEMBL9435314 | 0.83 | SERPINE1 (0.44) | SERPINE1KMT2ANPC1RAB9ACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994004513-A1 | PHARMACEUTICALLY ACTIVE DIKETOPIPERAZINES | XENOVA LIMITED (GB) | 1994-03-03 | — | — | WO | claimed |