Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 5/20 | 0.53 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SI | P14410 | 1/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | RAF1 | P04049 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | EP300 | Q09472 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9435603 | 1.00 | SERPINE1 (0.53) | SERPINE1MGAMGAASIMGAM2 | |
| SCHEMBL8641841 | 0.92 | SERPINE1 (0.56) | SERPINE1HRH3RAF1CYP1A2CDK1 | |
| SCHEMBL8641837 | 0.92 | SERPINE1 (0.56) | SERPINE1HRH3RAF1CYP1A2CDK1 | |
| SCHEMBL9435379 | 0.87 | SERPINE1 (0.52) | SERPINE1GAAHRH3MAPTMEN1 | |
| SCHEMBL9184625 | 0.87 | SERPINE1 (0.52) | SERPINE1GAAHRH3MAPTMEN1 | |
| SCHEMBL9435397 | 0.86 | SERPINE1 (0.53) | SERPINE1HRH3RAF1CYP1A2CDK1 | |
| SCHEMBL9187618 | 0.86 | SERPINE1 (0.53) | SERPINE1HRH3RAF1CYP1A2CDK1 | |
| SCHEMBL9435117 | 0.85 | SERPINE1 (0.50) | SERPINE1HRH3RAF1CYP1A2CDK1 | |
| SCHEMBL9435129 | 0.85 | SERPINE1 (0.50) | SERPINE1HRH3RAF1CYP1A2CDK1 | |
| SCHEMBL8639912 | 0.84 | SERPINE1 (0.68) | SERPINE1HRH3EP300MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994004513-A1 | PHARMACEUTICALLY ACTIVE DIKETOPIPERAZINES | XENOVA LIMITED (GB) | 1994-03-03 | — | — | WO | claimed |