Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.51 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.50 |
| ▸ | RARB | P10826 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9435152 | 1.00 | L3MBTL1 (0.57) | L3MBTL1KDM4EALDH1A1HPGDHTT | |
| SCHEMBL9435143 | 1.00 | L3MBTL1 (0.57) | L3MBTL1KDM4EALDH1A1HPGDHTT | |
| SCHEMBL9082992 | 0.93 | KDM4E (0.61) | L3MBTL1KDM4EALDH1A1HPGDHTT | |
| SCHEMBL9082997 | 0.90 | KDM4E (0.56) | L3MBTL1KDM4EALDH1A1HPGDHTT | |
| SCHEMBL9083783 | 0.90 | KDM4E (0.57) | L3MBTL1KDM4EALDH1A1HPGDHTT | |
| SCHEMBL9156630 | 0.89 | KDM4E (0.47) | L3MBTL1KDM4EALDH1A1HPGDHTT | |
| SCHEMBL9235964 | 0.87 | L3MBTL1 (0.48) | L3MBTL1KDM4EALDH1A1HPGDHTT | |
| SCHEMBL9237754 | 0.87 | L3MBTL1 (0.48) | L3MBTL1KDM4EALDH1A1HPGDHTT | |
| SCHEMBL9240392 | 0.87 | KDM4E (0.45) | L3MBTL1KDM4EALDH1A1HPGDHTT | |
| SCHEMBL9240990 | 0.87 | KDM4E (0.45) | L3MBTL1KDM4EALDH1A1HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5279762-A | High speed switching | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1994-01-18 | — | — | US | disclosed |
| EP-0220296-B1 | SMECTIC LIQUID CRYSTALLINE PHASES | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-07-28 | — | — | EP | disclosed |
| US-5064566-A | Chirally tilted, pyrimidines, pyridines, or pyrazines, stability | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-11-12 | — | — | US | disclosed |
| EP-0220296-A1 | SMECTIC LIQUID CRYSTALLINE PHASES. | MERCK PATENT GMBH (DE) | 1987-05-06 | — | — | EP | disclosed |
| WO-1986006401-A1 | SMECTIC LIQUID CRYSTALLINE PHASES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1986-11-06 | — | — | WO | disclosed |