Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 4/20 | 0.55 |
| ▸ | THRA | P10827 | 3/20 | 0.55 |
| ▸ | F2 | P00734 | 1/20 | 0.53 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.44 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9435191 | 1.00 | THRB (0.55) | THRBTHRAF2ITGB3ITGA2B | |
| SCHEMBL9189041 | 1.00 | THRB (0.55) | THRBTHRAF2ITGB3ITGA2B | |
| SCHEMBL9398371 | 0.99 | F2 (0.54) | THRBTHRAF2ITGB3ITGA2B | |
| SCHEMBL4651967 | 0.99 | F2 (0.54) | THRBTHRAF2ITGB3ITGA2B | |
| SCHEMBL9398375 | 0.99 | F2 (0.54) | THRBTHRAF2ITGB3ITGA2B | |
| SCHEMBL4651768 | 0.99 | F2 (0.54) | THRBTHRAF2ITGB3ITGA2B | |
| SCHEMBL10786522 | 0.97 | THRB (0.55) | THRBTHRAF2ITGB3ITGA2B | |
| SCHEMBL11244561 | 0.97 | THRB (0.55) | THRBTHRAF2ITGB3ITGA2B | |
| SCHEMBL22396364 | 0.97 | THRB (0.55) | THRBTHRAF2ITGB3ITGA2B | |
| SCHEMBL11416472 | 0.96 | THRB (0.52) | THRBTHRAF2ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5279762-A | High speed switching | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1994-01-18 | — | — | US | disclosed |
| US-5064566-A | Chirally tilted, pyrimidines, pyridines, or pyrazines, stability | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-11-12 | — | — | US | disclosed |