Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | MMP13 | P45452 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.46 |
| ▸ | CHRNG | P07510 | 1/20 | 0.46 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14054114 | 0.86 | CA1 (0.54) | HPGDPOLBALDH1A1CA1CA2 | |
| SCHEMBL9996871 | 0.86 | HPGD (0.48) | HPGDPOLBALDH1A1L3MBTL1KMT2A | |
| SCHEMBL16888470 | 0.85 | POLB (0.60) | HPGDPOLBHTTMMP13ALDH1A1 | |
| SCHEMBL9300437 | 0.84 | HPGD (0.60) | HPGDALDH1A1KMT2ATP53 | |
| SCHEMBL7886628 | 0.84 | HPGD (0.57) | HPGDPOLBHTTALDH1A1KDM4E | |
| SCHEMBL13753881 | 0.83 | HPGD (0.51) | HPGDALDH1A1L3MBTL1KMT2ACHRNA1 | |
| SCHEMBL4162822 | 0.83 | SMN1; SMN2 (0.57) | HPGDHTTALDH1A1KDM4ETP53 | |
| SCHEMBL12760708 | 0.83 | SMN1; SMN2 (0.57) | HPGDHTTALDH1A1KMT2ACHRNA1 | |
| SCHEMBL12553794 | 0.82 | HPGD (0.57) | HPGDPOLBHTTMMP13ALDH1A1 | |
| SCHEMBL9668044 | 0.82 | ESRRG (0.60) | HPGDPOLBHTTMMP13ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994015920-A1 | BENZANILIDE DERIVATIVES AS 5-HT1D-ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 1994-07-21 | — | — | WO | disclosed |