Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.60 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14435529 | 0.86 | HPGD (0.65) | HPGDTP53ALDH1A1MAPTKMT2A | |
| SCHEMBL12553807 | 0.85 | HPGD (0.60) | HPGDTP53ALDH1A1MAPTKMT2A | |
| SCHEMBL9435241 | 0.84 | HPGD (0.55) | HPGDTP53ALDH1A1KMT2A | |
| SCHEMBL15658862 | 0.84 | TP53 (0.67) | HPGDTP53ALDH1A1KMT2AMEN1 | |
| SCHEMBL9996871 | 0.83 | HPGD (0.48) | HPGDALDH1A1KMT2ANPC1RAB9A | |
| SCHEMBL14054114 | 0.83 | CA1 (0.54) | HPGDALDH1A1KMT2ANPC1RAB9A | |
| SCHEMBL436277 | 0.82 | KMT2A (0.55) | HPGDTP53ALDH1A1MAPTKMT2A | |
| SCHEMBL20662751 | 0.82 | TP53 (0.68) | HPGDTP53ALDH1A1KMT2AMEN1 | |
| SCHEMBL451696 | 0.81 | LMNA (0.54) | ALDH1A1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13753881 | 0.81 | HPGD (0.51) | HPGDALDH1A1MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5356893-A | Antidepressants, nervous system disorders | GLAXO GROUP LIMITED (GB) | 1994-10-18 | — | — | US | disclosed |
| EP-0533266-A1 | Benzanilide derivatives as 5-HT1D antagonists | GLAXO GROUP LIMITED (GB) | 1993-03-24 | — | — | EP | disclosed |