Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.71 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.56 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.54 |
| ▸ | HTR1D | P28221 | 1/20 | 0.51 |
| ▸ | KDM1A | O60341 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9435497 | 1.00 | OPRM1 (0.71) | OPRM1OPRL1CHRM4HTR1DKDM1A | |
| SCHEMBL5469271 | 0.86 | KMT2A (0.55) | OPRM1OPRL1HTR1D | |
| SCHEMBL5469268 | 0.86 | KMT2A (0.55) | OPRM1OPRL1HTR1D | |
| SCHEMBL5478395 | 0.86 | KMT2A (0.55) | OPRM1OPRL1HTR1D | |
| SCHEMBL476404 | 0.83 | OPRM1 (1.00) | OPRM1OPRL1CHRM4 | |
| SCHEMBL9435749 | 0.83 | OPRM1 (0.48) | OPRM1KDM1A | |
| SCHEMBL9435756 | 0.83 | OPRM1 (0.48) | OPRM1KDM1A | |
| SCHEMBL23798654 | 0.82 | OPRL1 (0.56) | OPRM1OPRL1KDM1A | |
| Hydrochloric Acid SCHEMBL2473959 | 0.82 | OPRM1 (0.97) | OPRM1OPRL1CHRM4 | |
| SCHEMBL8052905 | 0.81 | OPRM1 (0.69) | OPRM1OPRL1CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5371088-A | 1-aryl-4-piperazinylcyclohexanecarbonitriles, the preparation and use thereof | BASF AKTIENGESELLSCHAFT (DE) | 1994-12-06 | — | — | US | disclosed |