Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 15/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8904425 | 0.89 | CCKBR (0.61) | CCKBRALDH1A1MAPT | |
| SCHEMBL8903356 | 0.89 | CCKBR (0.60) | CCKBR | |
| SCHEMBL8903101 | 0.85 | CCKBR (0.60) | CCKBR | |
| SCHEMBL8904274 | 0.85 | CCKBR (0.60) | CCKBRALDH1A1MAPT | |
| SCHEMBL8904296 | 0.85 | CCKBR (0.60) | CCKBR | |
| SCHEMBL8903106 | 0.85 | CCKBR (0.60) | CCKBR | |
| SCHEMBL8904532 | 0.85 | CCKBR (0.62) | CCKBR | |
| SCHEMBL9435384 | 0.85 | CCKBR (0.60) | CCKBR | |
| SCHEMBL8905032 | 0.83 | CCKBR (0.57) | CCKBRALDH1A1MAPT | |
| SCHEMBL8905038 | 0.83 | CCKBR (0.57) | CCKBRALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994001421-A1 | BENZOTHIAZEPINE AND BENZOXAZEPINE DERIVATIVES AS CHOLECYSTOKININ RECEPTOR ANTAGONISTS | PFIZER INC. (US) | 1994-01-20 | — | — | WO | disclosed |