Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | APP | P05067 | 4/20 | 0.41 |
| ▸ | SNCA | P37840 | 4/20 | 0.41 |
| ▸ | METAP1 | P53582 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PLEC | Q15149 | 1/20 | 0.38 |
| ▸ | BRAF | P15056 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9187329 | 1.00 | SERPINE1 (0.50) | SERPINE1MAOBMAPTAPPSNCA | |
| SCHEMBL8641841 | 0.87 | SERPINE1 (0.56) | SERPINE1MAOBMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL8641837 | 0.87 | SERPINE1 (0.56) | SERPINE1MAOBMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL9435600 | 0.82 | SERPINE1 (0.53) | SERPINE1MAOBMAPTMEN1KMT2A | |
| SCHEMBL9435397 | 0.82 | SERPINE1 (0.53) | SERPINE1MAOBMEN1KMT2ARAB9A | |
| SCHEMBL9435603 | 0.82 | SERPINE1 (0.53) | SERPINE1MAOBMAPTMEN1KMT2A | |
| SCHEMBL9187618 | 0.82 | SERPINE1 (0.53) | SERPINE1MAOBMEN1KMT2ARAB9A | |
| SCHEMBL6379198 | 0.81 | SERPINE1 (0.56) | SERPINE1MAOBMAPTAPPSNCA | |
| SCHEMBL6379195 | 0.81 | SERPINE1 (0.56) | SERPINE1MAOBMAPTAPPSNCA | |
| SCHEMBL1166080 | 0.80 | SERPINE1 (0.68) | SERPINE1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994004513-A1 | PHARMACEUTICALLY ACTIVE DIKETOPIPERAZINES | XENOVA LIMITED (GB) | 1994-03-03 | — | — | WO | disclosed |