Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 4/20 | 0.41 |
| ▸ | CTSK | P43235 | 4/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28888489 | 1.00 | KMT2A (0.58) | KMT2AMEN1GAATDP1EPHX1 | |
| SCHEMBL2402827 | 0.90 | MEN1 (0.64) | KMT2AMEN1GAATDP1EPHX1 | |
| SCHEMBL14206399 | 0.85 | CA12 (0.50) | KMT2AMEN1GAATDP1EPHX1 | |
| SCHEMBL2153082 | 0.85 | CA12 (0.50) | KMT2AMEN1GAATDP1EPHX1 | |
| SCHEMBL15356413 | 0.84 | KMT2A (0.51) | KMT2AMEN1GAATDP1EPHX1 | |
| SCHEMBL1319912 | 0.84 | MEN1 (0.54) | KMT2AMEN1GAATDP1EPHX1 | |
| SCHEMBL12464151 | 0.83 | TDP1 (0.50) | KMT2AMEN1GAATDP1EPHX1 | |
| SCHEMBL1022917 | 0.83 | KMT2A (0.47) | KMT2AMEN1GAATDP1EPHX1 | |
| SCHEMBL16151966 | 0.83 | MEN1 (0.55) | KMT2AMEN1GAATDP1EPHX1 | |
| SCHEMBL8977043 | 0.82 | MEN1 (0.54) | KMT2AMEN1GAATDP1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108129404-B | Synthesis method of chiral piperazinone derivative | 凯瑞斯德生化(苏州)有限公司 | 2020-05-01 | — | — | CN | disclosed |
| EP-0618923-A1 | PEPTIDE NUCLEIC ACIDS AND THEIR EFFECT ON GENETIC MATERIAL | GLAXO WELLCOME INC. (US) | 1994-10-12 | — | — | EP | disclosed |
| WO-1993012129-A1 | PEPTIDE NUCLEIC ACIDS AND THEIR EFFECT ON GENETIC MATERIAL | GLAXO INC. (US) | 1993-06-24 | — | — | WO | disclosed |