Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | CTSL | P07711 | 2/20 | 0.52 |
| ▸ | CTSB | P07858 | 1/20 | 0.52 |
| ▸ | CTSS | P25774 | 1/20 | 0.52 |
| ▸ | CTSK | P43235 | 1/20 | 0.52 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7460122 | 0.86 | CTSL (0.48) | MEN1KMT2AGAACTSLCTSB | |
| SCHEMBL4342005 | 0.84 | CAPN1 (0.47) | MEN1KMT2AGAACTSLCTSB | |
| SCHEMBL21312432 | 0.84 | MEN1 (0.57) | MEN1KMT2AGAACTSLCTSB | |
| SCHEMBL8017285 | 0.84 | CAPN1 (0.46) | MEN1KMT2AGAACTSLCTSB | |
| SCHEMBL5921648 | 0.83 | MEN1 (0.55) | MEN1KMT2AGAACTSSCTSK | |
| SCHEMBL9980668 | 0.82 | CAPN1 (0.54) | MEN1KMT2AGAACTSLCTSB | |
| SCHEMBL28888489 | 0.82 | KMT2A (0.58) | MEN1KMT2AGAACTSLCTSB | |
| SCHEMBL9435405 | 0.82 | KMT2A (0.58) | MEN1KMT2AGAACTSLCTSB | |
| SCHEMBL10726270 | 0.81 | CTSL (0.56) | MEN1KMT2ACTSLCTSBCTSS | |
| SCHEMBL17559 | 0.80 | CTSL (0.66) | MEN1KMT2ACTSLCTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0706532-A1 | NEW COMPOUND AND ITS PREPARATION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-04-17 | — | — | EP | disclosed |