Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.43 |
| ▸ | XDH | P47989 | 2/20 | 0.41 |
| ▸ | TDP2 | O95551 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | CASP9 | P55211 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9187972 | 1.00 | SERPINE1 (0.52) | SERPINE1ALDH1A1MAPTKDM4ECYP19A1 | |
| SCHEMBL9435639 | 0.96 | SERPINE1 (0.49) | SERPINE1ALDH1A1MAPTKDM4ECYP19A1 | |
| SCHEMBL9183923 | 0.96 | SERPINE1 (0.49) | SERPINE1ALDH1A1MAPTKDM4ECYP19A1 | |
| SCHEMBL6378946 | 0.85 | SERPINE1 (0.69) | SERPINE1ALDH1A1MAPTKDM4ECYP19A1 | |
| SCHEMBL6378954 | 0.85 | SERPINE1 (0.69) | SERPINE1ALDH1A1MAPTKDM4ECYP19A1 | |
| SCHEMBL1166080 | 0.85 | SERPINE1 (0.68) | SERPINE1MAPT | |
| SCHEMBL8639912 | 0.85 | SERPINE1 (0.68) | SERPINE1MAPT | |
| SCHEMBL1166081 | 0.85 | SERPINE1 (0.68) | SERPINE1MAPT | |
| SCHEMBL8639908 | 0.85 | SERPINE1 (0.68) | SERPINE1MAPT | |
| SCHEMBL9435404 | 0.78 | SERPINE1 (0.50) | SERPINE1MAPTKMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994004513-A1 | PHARMACEUTICALLY ACTIVE DIKETOPIPERAZINES | XENOVA LIMITED (GB) | 1994-03-03 | — | — | WO | claimed |
| WO-1994004513-A1 | PHARMACEUTICALLY ACTIVE DIKETOPIPERAZINES | XENOVA LIMITED (GB) | 1994-03-03 | — | — | WO | disclosed |