⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23475924 | 0.76 | TSHR (0.44) | — | |
| SCHEMBL2447138 | 0.72 | — | — | |
| SCHEMBL18470774 | 0.72 | — | — | |
| SCHEMBL16015581 | 0.70 | — | — | |
| SCHEMBL23735557 | 0.67 | NPSR1 (0.38) | — | |
| SCHEMBL31478239 | 0.67 | — | — | |
| SCHEMBL16807522 | 0.67 | — | — | |
| SCHEMBL23987888 | 0.66 | HSP90AA1 (0.52) | — | |
| SCHEMBL23988250 | 0.66 | HDAC3 (0.34) | — | |
| SCHEMBL182913 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5374516-A | Covalently attached to polymer particles of ethylenically unsaturated monomers with reactive alkylsulfonyl or halogen groups; detecting hormones, drugs, steroids in urine, blood, saliva | EASTMAN KODAK COMPANY (US) | 1994-12-20 | — | — | US | disclosed |
| EP-0302715-B1 | AVIDIN- AND BIOTIN-IMMOBILIZED REAGENTS, ANALYTICAL ELEMENTS AND METHODS OF USE | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1992-04-22 | — | — | EP | disclosed |
| EP-0370694-A2 | Diagnostic kit and method using a solid phase capture means for detecting nucleic acids | EASTMAN KODAK COMPANY (US) | 1990-05-30 | — | — | EP | disclosed |
| EP-0302715-A1 | Avidin- and biotin-immobilized reagents, analytical elements and methods of use | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1989-02-08 | — | — | EP | disclosed |