Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | PPM1B | O75688 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 2/20 | 0.35 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | CTSG | P08311 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29902551 | 1.00 | TSHR (0.47) | TSHRPPM1BPTPN1PPP1CCALDH1A1 | |
| SCHEMBL9127580 | 1.00 | TSHR (0.47) | TSHRPPM1BPTPN1PPP1CCALDH1A1 | |
| SCHEMBL14967565 | 0.85 | TSHR (0.49) | TSHRPPM1BPTPN1PPP1CCALDH1A1 | |
| SCHEMBL17708321 | 0.85 | TSHR (0.49) | TSHRPPM1BPTPN1PPP1CCALDH1A1 | |
| SCHEMBL27737603 | 0.85 | LGALS3 (0.46) | TSHRPPM1BPTPN1PPP1CCALDH1A1 | |
| SCHEMBL13046117 | 0.82 | TSHR (0.46) | TSHRPPM1BPTPN1PPP1CCALDH1A1 | |
| SCHEMBL13046140 | 0.82 | TSHR (0.46) | TSHRPPM1BPTPN1PPP1CCALDH1A1 | |
| SCHEMBL19974946 | 0.82 | TSHR (0.46) | TSHRPPM1BPTPN1PPP1CCALDH1A1 | |
| SCHEMBL11545787 | 0.80 | TSHR (0.55) | TSHRPPM1BPTPN1PPP1CCALDH1A1 | |
| SCHEMBL5317413 | 0.80 | TSHR (0.55) | TSHRPPM1BPTPN1PPP1CCALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5296615-A | Process and intermediates for chiral epoxides | ELI LILLY AND COMPANY (US) | 1994-03-22 | — | — | US | disclosed |
| US-5256807-A | Process and intermediates for chiral epoxides | ELI LILLY AND COMPANY (US) | 1993-10-26 | — | — | US | disclosed |
| US-5183910-A | Process and intermediates for chiral epoxides | ELI LILLY AND COMPANY (US) | 1993-02-02 | — | — | US | disclosed |
| US-5097049-A | PROCESS AND INTERMEDIATES FOR CHIRAL EPOXIDES | ELI LILLY AND COMPANY (US) | 1992-03-17 | — | — | US | disclosed |
| EP-0455473-A1 | Process and intermediates for chiral epoxides | ELI LILLY AND COMPANY (US) | 1991-11-06 | — | — | EP | disclosed |