Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ERAP1 | Q9NZ08 | 3/20 | 0.45 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9190265 | 0.85 | SLC9A1 (0.68) | KMT2ASLC9A1 | |
| SCHEMBL11710362 | 0.80 | SMN1; SMN2 (0.62) | SMN1; SMN2TDP1GAAPOLBL3MBTL1 | |
| SCHEMBL11184578 | 0.79 | TDP1 (0.67) | SMN1; SMN2TDP1POLBL3MBTL1KMT2A | |
| SCHEMBL3677981 | 0.79 | SMN1; SMN2 (0.48) | SMN1; SMN2TDP1POLBKMT2AMEN1 | |
| SCHEMBL8086640 | 0.79 | SMN1; SMN2 (0.48) | SMN1; SMN2TDP1POLBKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL11714616 | 0.79 | SMN1; SMN2 (0.61) | SMN1; SMN2TDP1GAAPOLBL3MBTL1 | |
| SCHEMBL9436719 | 0.79 | SLC9A1 (0.68) | SMN1; SMN2TDP1GAAKDM4EPOLB | |
| SCHEMBL11711961 | 0.78 | SMN1; SMN2 (0.64) | SMN1; SMN2TDP1GAAL3MBTL1LMNA | |
| Hydrochloric Acid SCHEMBL11711399 | 0.77 | SMN1; SMN2 (0.62) | SMN1; SMN2TDP1GAAL3MBTL1LMNA | |
| SCHEMBL9196797 | 0.77 | SLC9A1 (0.66) | SMN1; SMN2TDP1GAAKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5292755-A | USPA benzolyguanidines | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-03-08 | — | — | US | disclosed |
| US-5091394-A | BENZOYLGUANIDINES, A PROCESS FOR THEIR PREPARATION, THEIR USE AS MEDICAMENTS AND MEDICAMENTS CONTAINING THEM | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-02-25 | — | — | US | disclosed |