Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | ERAP1 | Q9NZ08 | 7/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11713016 | 0.88 | ERAP1 (0.48) | GAAMEN1KMT2AERAP1KDM4E | |
| SCHEMBL9436763 | 0.85 | MAPT (0.55) | GAAMEN1KMT2AERAP1KDM4E | |
| Hydrochloric Acid SCHEMBL9436766 | 0.84 | SLC9A1 (0.68) | SLC9A1 | |
| Hydrochloric Acid SCHEMBL9189932 | 0.83 | SLC9A1 (0.45) | GAAMEN1KMT2AKDM4ETDP1 | |
| SCHEMBL9436694 | 0.83 | NPSR1 (0.56) | GAAMEN1KMT2AERAP1KDM4E | |
| SCHEMBL11710944 | 0.80 | ERAP1 (0.50) | GAAMEN1KMT2AERAP1KDM4E | |
| SCHEMBL9436719 | 0.79 | SLC9A1 (0.68) | GAAMEN1KMT2AERAP1KDM4E | |
| SCHEMBL9196821 | 0.79 | SLC9A1 (0.67) | ALDH1A1SLC9A1 | |
| SCHEMBL9196797 | 0.78 | SLC9A1 (0.66) | GAAMEN1KMT2AERAP1KDM4E | |
| SCHEMBL9196817 | 0.78 | SLC9A1 (0.44) | GAAMEN1KMT2AKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5292755-A | USPA benzolyguanidines | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-03-08 | — | — | US | disclosed |
| US-5091394-A | BENZOYLGUANIDINES, A PROCESS FOR THEIR PREPARATION, THEIR USE AS MEDICAMENTS AND MEDICAMENTS CONTAINING THEM | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-02-25 | — | — | US | disclosed |