Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 3/20 | 0.52 |
| ▸ | FDPS | P14324 | 4/20 | 0.47 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.44 |
| ▸ | LAP3 | P28838 | 1/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2248856 | 1.00 | SMPD1 (0.52) | SMPD1FDPSS1PR2S1PR1S1PR3 | |
| SCHEMBL3813283 | 1.00 | SMPD1 (0.52) | SMPD1FDPSS1PR2S1PR1S1PR3 | |
| SCHEMBL2251176 | 1.00 | SMPD1 (0.52) | SMPD1FDPSS1PR2S1PR1S1PR3 | |
| SCHEMBL674654 | 1.00 | SMPD1 (0.52) | SMPD1FDPSS1PR2S1PR1S1PR3 | |
| SCHEMBL3818501 | 0.98 | SMPD1 (0.48) | SMPD1FDPSS1PR2S1PR1S1PR3 | |
| SCHEMBL3817199 | 0.94 | SMPD1 (0.47) | SMPD1FDPSS1PR2S1PR1S1PR3 | |
| SCHEMBL3818577 | 0.92 | FDPS (0.45) | SMPD1FDPSS1PR2S1PR1S1PR3 | |
| SCHEMBL16569788 | 0.92 | FDPS (0.45) | SMPD1FDPSS1PR2S1PR1S1PR3 | |
| SCHEMBL3815094 | 0.92 | SMPD1 (0.48) | SMPD1FDPSS1PR2S1PR1S1PR3 | |
| SCHEMBL3814007 | 0.91 | CYP3A4 (0.45) | SMPD1FDPSTRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0437347-B1 | Topical composition | UNILEVER PLC (GB) | 1994-04-13 | — | — | EP | claimed |
| EP-0437347-A1 | Topical composition | UNILEVER PLC (GB) | 1991-07-17 | — | — | EP | claimed |
| EP-0437347-B1 | Topical composition | UNILEVER PLC (GB) | 1994-04-13 | — | — | EP | disclosed |
| EP-0437347-A1 | Topical composition | UNILEVER PLC (GB) | 1991-07-17 | — | — | EP | disclosed |