Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 10/20 | 0.75 |
| ▸ | LMNA | P02545 | 2/20 | 0.75 |
| ▸ | NR3C1 | P04150 | 7/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.72 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.72 |
| ▸ | PGR | P06401 | 2/20 | 0.72 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.72 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.72 |
| ▸ | MAPT | P10636 | 2/20 | 0.72 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.72 |
| ▸ | SHBG | P04278 | 1/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.72 |
| ▸ | AR | P10275 | 1/20 | 0.66 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.66 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11814284 | 0.92 | HIF1A (0.81) | HIF1ALMNANR3C1SMN1; SMN2CYP2C19 | |
| SCHEMBL10991253 | 0.91 | HIF1A (0.70) | HIF1ALMNANR3C1SMN1; SMN2CYP2C19 | |
| SCHEMBL16020569 | 0.90 | HIF1A (0.78) | HIF1ALMNANR3C1SMN1; SMN2CYP2C19 | |
| SCHEMBL7614974 | 0.90 | HIF1A (0.77) | HIF1ALMNANR3C1SMN1; SMN2CYP2C19 | |
| SCHEMBL8071547 | 0.90 | HIF1A (0.77) | HIF1ALMNANR3C1SMN1; SMN2CYP2C19 | |
| SCHEMBL2484782 | 0.88 | HIF1A (0.84) | HIF1ALMNANR3C1SMN1; SMN2CYP2C19 | |
| SCHEMBL13147966 | 0.88 | HIF1A (0.84) | HIF1ALMNANR3C1SMN1; SMN2CYP2C19 | |
| SCHEMBL1626384 | 0.88 | HIF1A (0.84) | HIF1ALMNANR3C1SMN1; SMN2CYP2C19 | |
| SCHEMBL1626382 | 0.88 | HIF1A (0.84) | HIF1ALMNANR3C1SMN1; SMN2CYP2C19 | |
| SCHEMBL13043685 | 0.88 | HIF1A (0.84) | HIF1ALMNANR3C1SMN1; SMN2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113504328-A | High-flux detection method for glucocorticoid and sex hormone in cosmetics | 苏州市药品检验检测研究中心 | 2021-10-15 | — | — | CN | disclosed |
| US-5352808-A | Process for steroid preparation | ROUSSEL UCLAF (FR) | 1994-10-04 | — | — | US | disclosed |