Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 10/20 | 0.77 |
| ▸ | LMNA | P02545 | 2/20 | 0.77 |
| ▸ | NR3C1 | P04150 | 7/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.73 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.73 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.73 |
| ▸ | PGR | P06401 | 2/20 | 0.73 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.73 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.73 |
| ▸ | MAPT | P10636 | 2/20 | 0.73 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.73 |
| ▸ | SHBG | P04278 | 1/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.73 |
| ▸ | AR | P10275 | 1/20 | 0.67 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.67 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11814284 | 0.93 | HIF1A (0.81) | HIF1ALMNANR3C1SMN1; SMN2CYP2C19 | |
| SCHEMBL16020569 | 0.91 | HIF1A (0.78) | HIF1ALMNANR3C1SMN1; SMN2CYP2C19 | |
| SCHEMBL7614974 | 0.90 | HIF1A (0.77) | HIF1ALMNANR3C1SMN1; SMN2CYP2C19 | |
| SCHEMBL9437393 | 0.90 | HIF1A (0.75) | HIF1ALMNANR3C1SMN1; SMN2CYP2C19 | |
| SCHEMBL29064801 | 0.88 | HIF1A (0.73) | HIF1ALMNANR3C1SMN1; SMN2CYP2C19 | |
| SCHEMBL7519660 | 0.87 | HIF1A (0.75) | HIF1ALMNANR3C1SMN1; SMN2CYP2C19 | |
| SCHEMBL607956 | 0.87 | HIF1A (0.72) | HIF1ALMNANR3C1SMN1; SMN2CYP2C19 | |
| SCHEMBL14523057 | 0.87 | HIF1A (1.00) | HIF1ALMNANR3C1SMN1; SMN2CYP2C19 | |
| SCHEMBL139280 | 0.87 | HIF1A (1.00) | HIF1ALMNANR3C1SMN1; SMN2CYP2C19 | |
| SCHEMBL1626384 | 0.87 | HIF1A (0.84) | HIF1ALMNANR3C1SMN1; SMN2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0665238-B1 | Corticoid derivatives and pharmaceutical and cosmetic compositions | SENJU PHARMA CO (JP) | 2000-08-09 | — | — | EP | disclosed |
| US-5776922-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS, CATARACT AND ANTIISCHEMIC ORGAN DISEASE | SENJU PHARMACEUTICAL CO., LTD. (JP) | 1998-07-07 | — | — | US | disclosed |
| EP-0659763-B1 | 21-Hydroxy pregnane - Quinoline carboxylic acid esters and Antibacterial and Antiinflammatory compositions containing them | SENJU PHARMA CO (JP) | 1998-05-20 | — | — | EP | disclosed |
| US-5599807-A | BACTERICIDE, ANTIINFLAMMATORY AGENT | SENJU PHARMACEUTICAL CO., LTD. (JP) | 1997-02-04 | — | — | US | disclosed |
| EP-0665238-A1 | Corticoid derivatives and pharmaceutical and cosmetic compositions | Senju Pharmaceutical Co., Ltd. (JP) | 1995-08-02 | — | — | EP | disclosed |
| EP-0659763-A2 | Steroid derivatives | Senju Pharmaceutical Co., Ltd. (JP) | 1995-06-28 | — | — | EP | disclosed |
| EP-0124233-A2 | 21-Hydroxycorticosteroid esters, and compositions containing them | THE UPJOHN COMPANY (US) | 1984-11-07 | — | — | EP | disclosed |
| US-4469689-A | WATER SOLUBLE, ANTIINFLAMMATORY AGENTS | THE UPJOHN COMPANY (US) | 1984-09-04 | — | — | US | disclosed |
| US-4443440-A | ANTIINFLAMMATORY AGENTS | THE UPJOHN COMPANY (US) | 1984-04-17 | — | — | US | disclosed |
| EP-0104746-A1 | 21-Hydroxycorticosteroid esters, and compositions containing them | THE UPJOHN COMPANY (US) | 1984-04-04 | — | — | EP | disclosed |