Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 4/20 | 0.68 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | F2 | P00734 | 3/20 | 0.49 |
| ▸ | F10 | P00742 | 1/20 | 0.49 |
| ▸ | PLG | P00747 | 1/20 | 0.49 |
| ▸ | PLAU | P00749 | 1/20 | 0.49 |
| ▸ | PLAT | P00750 | 1/20 | 0.49 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.49 |
| ▸ | DAPK3 | O43293 | 3/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.48 |
| ▸ | MASP2 | O00187 | 1/20 | 0.47 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.47 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.47 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9437540 | 1.00 | NOTUM (0.68) | NOTUMADRA1AF2F10PLG | |
| SCHEMBL24763252 | 0.89 | NOTUM (0.62) | NOTUMADRA1AF2F10PLG | |
| SCHEMBL29518083 | 0.86 | NOTUM (0.59) | NOTUMADRA1AF2F10PLG | |
| SCHEMBL22505804 | 0.86 | NOTUM (0.59) | NOTUMADRA1AF2F10PLG | |
| SCHEMBL24241662 | 0.82 | NOTUM (0.64) | NOTUMADRA1AF2MAPTMASP2 | |
| SCHEMBL22505214 | 0.80 | NOTUM (0.61) | NOTUMADRA1AF2F10PLG | |
| SCHEMBL3585257 | 0.79 | DAPK3 (0.57) | NOTUMF2F10PLGPLAU | |
| SCHEMBL3585256 | 0.79 | DAPK3 (0.57) | NOTUMF2F10PLGPLAU | |
| SCHEMBL3585803 | 0.79 | DAPK3 (0.57) | NOTUMF2F10PLGPLAU | |
| SCHEMBL28342551 | 0.79 | F2 (0.64) | NOTUMF2F10PLGPLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5340802-A | Central nervous system disorders | ABBOTT LABORATORIES (US) | 1994-08-23 | — | — | US | disclosed |
| EP-0405506-A1 | Tetrapeptide type-B CCK receptor ligands | ABBOTT LABORATORIES (US) | 1991-01-02 | — | — | EP | disclosed |