Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | REN | P00797 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | MMP2 | P08253 | 4/20 | 0.35 |
| ▸ | MMP9 | P14780 | 3/20 | 0.35 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9437655 | 0.88 | HSD17B10 (0.40) | KMT2ARENMEN1ALDH1A1 | |
| SCHEMBL9437602 | 0.87 | F2 (0.36) | KMT2AMEN1ALDH1A1MMP2MMP9 | |
| SCHEMBL9437588 | 0.84 | CHRM1 (0.41) | KMT2ARENMEN1ALDH1A1 | |
| SCHEMBL9437560 | 0.80 | KMT2A (0.41) | KMT2ARENMEN1ALDH1A1ITGB3 | |
| SCHEMBL9437654 | 0.78 | KMT2A (0.41) | KMT2ARENMEN1ALDH1A1ITGB3 | |
| SCHEMBL9437535 | 0.78 | REN (0.41) | KMT2ARENMEN1ALDH1A1ITGB3 | |
| SCHEMBL9437605 | 0.77 | KMT2A (0.40) | KMT2ARENMEN1ALDH1A1ITGB3 | |
| SCHEMBL9437542 | 0.77 | REN (0.41) | KMT2ARENMEN1ALDH1A1ITGB3 | |
| SCHEMBL7331751 | 0.71 | REN (0.54) | REN | |
| SCHEMBL9437590 | 0.70 | KMT2A (0.37) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332742-A | Ocular hypotensive | ABBOTT LABORATORIES (US) | 1994-07-26 | — | — | US | disclosed |