Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 5/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 2/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16967812 | 1.00 | MEN1 (0.44) | MEN1GAAKMT2ATDP1CTSK | |
| SCHEMBL27397806 | 1.00 | MEN1 (0.44) | MEN1GAAKMT2ATDP1CTSK | |
| SCHEMBL14941209 | 0.84 | CTSK (0.49) | MEN1GAAKMT2ATDP1CTSK | |
| SCHEMBL23572511 | 0.83 | MEN1 (0.53) | MEN1GAAKMT2ATDP1CTSK | |
| SCHEMBL22644678 | 0.83 | MEN1 (0.41) | MEN1GAAKMT2ATDP1CTSK | |
| SCHEMBL12621511 | 0.82 | MEN1 (0.44) | MEN1GAAKMT2ATDP1CTSK | |
| SCHEMBL27504224 | 0.82 | MEN1 (0.44) | MEN1GAAKMT2ATDP1CTSK | |
| SCHEMBL18508305 | 0.82 | MEN1 (0.44) | MEN1GAAKMT2ATDP1CTSK | |
| SCHEMBL6339388 | 0.80 | MEN1 (0.62) | MEN1GAAKMT2ATDP1CA1 | |
| SCHEMBL21293800 | 0.79 | MEN1 (0.47) | MEN1GAAKMT2ATDP1CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106661084-B | Macrocyclic broad spectrum antibiotics | 阿奇克斯制药公司 | 2021-08-31 | — | — | CN | disclosed |
| WO-2015179441-A2 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | RQX PHARMACEUTICALS, INC. (US) | 2015-11-26 | — | — | WO | disclosed |
| US-5340802-A | Central nervous system disorders | ABBOTT LABORATORIES (US) | 1994-08-23 | — | — | US | disclosed |
| EP-0405506-A1 | Tetrapeptide type-B CCK receptor ligands | ABBOTT LABORATORIES (US) | 1991-01-02 | — | — | EP | disclosed |