Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7334317 | 0.92 | REN (0.64) | REN | |
| SCHEMBL7331904 | 0.81 | REN (0.66) | REN | |
| SCHEMBL9226527 | 0.77 | REN (0.68) | REN | |
| SCHEMBL7267778 | 0.77 | REN (0.66) | REN | |
| SCHEMBL7278183 | 0.76 | REN (0.57) | REN | |
| SCHEMBL7306850 | 0.76 | REN (0.67) | REN | |
| SCHEMBL9741492 | 0.75 | REN (0.52) | REN | |
| SCHEMBL9224297 | 0.75 | REN (0.52) | REN | |
| SCHEMBL9437639 | 0.75 | REN (0.56) | REN | |
| SCHEMBL7327976 | 0.74 | REN (0.67) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5360791-A | Renin-inhibiting aminodiol derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-11-01 | — | — | US | disclosed |