SCHEMBL9438166

SCHEMBL9438166

O=C(OOOOOC(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.76
F2 P00734 1/20 0.76
TSHR P16473 6/20 0.57
ALDH1A1 P00352 4/20 0.57
TDP1 Q9NUW8 4/20 0.57
HSD17B10 Q99714 2/20 0.57
TP53 P04637 1/20 0.50
KMT2A Q03164 3/20 0.48
MAPT P10636 3/20 0.48
POLB P06746 2/20 0.48
MAPK1 P28482 1/20 0.48
HIF1A Q16665 1/20 0.48
SLC6A2 P23975 1/20 0.48
SLC6A3 Q01959 1/20 0.48
CES2 O00748 2/20 0.48
CES1 P23141 2/20 0.48
DAO P14920 1/20 0.48
NAPRT Q6XQN6 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.47
CYP3A4 P08684 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5173689 0.97 LMNA (0.80) LMNAF2TSHRALDH1A1TDP1
SCHEMBL991333 0.92 LMNA (0.80) LMNAF2TSHRALDH1A1TDP1
Ammonia Solution, Strong SCHEMBL9421536 0.90 LMNA (0.76) LMNAF2TSHRALDH1A1TDP1
Benzoyl Peroxide SCHEMBL2929886 0.87 LMNA (1.00) LMNAF2TSHRALDH1A1TDP1
Benzoyl Peroxide SCHEMBL5312311 0.87 LMNA (1.00) LMNAF2TSHRALDH1A1TDP1
Benzoyl Peroxide SCHEMBL63 0.87 LMNA (1.00) LMNAF2TSHRALDH1A1TDP1
Benzoyl Peroxide SCHEMBL9407293 0.87 LMNA (1.00) LMNAF2TSHRALDH1A1TDP1
Benzoyl Peroxide SCHEMBL3467853 0.87 LMNA (1.00) LMNAF2TSHRALDH1A1TDP1
SCHEMBL28496662 0.86 LMNA (0.70) LMNAF2TSHRALDH1A1TDP1
SCHEMBL4607118 0.86 LMNA (0.70) LMNAF2TSHRALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0279430-B1 The method of manufacturing a grafted resin composition NIPPON OILS & FATS CO LTD (JP) 1994-06-15 EP disclosed
US-4839432-A USING A UNSATURATED PEROXY FREE RADICAL CATALYSTS NIPPON OIL AND FATS CO., LTD. (JP) 1989-06-13 US disclosed
EP-0279430-A2 The method of manufacturing a grafted resin composition NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1988-08-24 EP disclosed