Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.49 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | UNG | P13051 | 3/20 | 0.44 |
| ▸ | IDH1 | O75874 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1476038 | 0.93 | HPGD (0.50) | HPGDUNGMAPTMEN1NPC1 | |
| SCHEMBL29699621 | 0.88 | UNG (0.51) | HPGDUNGMAPTMEN1NPC1 | |
| SCHEMBL13856898 | 0.87 | UNG (0.53) | UNGMAPTMEN1NPC1LMNA | |
| SCHEMBL13962364 | 0.87 | UNG (0.53) | UNGMAPTMEN1NPC1LMNA | |
| SCHEMBL9129626 | 0.84 | NPC1 (0.61) | HPGDUNGMAPTMEN1NPC1 | |
| SCHEMBL10732288 | 0.83 | NPC1 (0.62) | HPGDMAPTMEN1NPC1LMNA | |
| SCHEMBL1476567 | 0.82 | MAPT (0.52) | HPGDUNGMAPTMEN1NPC1 | |
| SCHEMBL10587639 | 0.81 | LMNA (0.44) | MAPTMEN1NPC1LMNAMAPK1 | |
| SCHEMBL14507795 | 0.80 | HPGD (0.40) | HPGDUNGMAPTMEN1NPC1 | |
| SCHEMBL1476804 | 0.79 | HPGD (0.44) | HPGDUNGMAPTMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5342974-A | Reacting 1,4,5,8-tetrachloroanthraquione with monohalogenated aniline in presence of carboxylic acid salt, benzyl alcohol and copper catalyst | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1994-08-30 | — | — | US | disclosed |
| EP-0323184-B1 | Halogenated anthraquinones useful as near infrared absorbing optical filters, and method of making them | MITSUI TOATSU CHEMICALS (JP) | 1994-03-09 | — | — | EP | disclosed |
| EP-0323184-A1 | Halogenated anthraquinones useful as near infrared absorbing optical filters, and method of making them | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1989-07-05 | — | — | EP | disclosed |