Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL16909948 | 0.94 | OR51E2 (0.40) | OR51E2KDM4ETSHRALOX15HSD17B10 | |
| Oxalic Acid SCHEMBL6245793 | 0.91 | OR51E2 (0.42) | OR51E2KDM4ETSHRALOX15ALDH1A1 | |
| Glycolic Acid SCHEMBL5074477 | 0.88 | OR51E2 (0.37) | OR51E2KDM4ETSHRALOX15HSD17B10 | |
| Glycolic Acid SCHEMBL28620464 | 0.85 | OR51E2 (0.35) | OR51E2KDM4ETSHRALOX15ALDH1A1 | |
| Glycolic Acid SCHEMBL9764167 | 0.85 | — | — | |
| Oxalic Acid SCHEMBL9062722 | 0.85 | TSHR (0.38) | TSHR | |
| Oxalic Acid SCHEMBL1028515 | 0.78 | OR51E2 (0.53) | OR51E2TSHRALOX15ALDH1A1CYP2D6 | |
| Oxalic Acid SCHEMBL8986242 | 0.78 | TSHR (0.43) | KDM4ETSHRALDH1A1 | |
| Glycolic Acid SCHEMBL9701427 | 0.77 | FFAR3 (0.44) | OR51E2KDM4ETSHRALOX15ALDH1A1 | |
| Glyoxylate SCHEMBL2352268 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0611399-A1 | HYDROGENATION OF ENZYMATICALLY-PRODUCED GLYOXYLIC ACID/AMINOMETHYL-PHOSPHONIC ACID MIXTURES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-08-24 | — | — | EP | disclosed |
| EP-0611398-A1 | ENZYMATIC PREPARATION OF N-(PHOSPHONOMETHYL)GLYCINE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-08-24 | — | — | EP | disclosed |
| US-5262314-A | Enzymatic oxidation of glycolic acid in the presence of non-enzymatic catalyst for decomposing hydrogen peroxide | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-11-16 | — | — | US | disclosed |
| WO-1993009243-A1 | HYDROGENATION OF ENZYMATICALLY-PRODUCED GLYOXYLIC ACID/AMINOMETHYL-PHOSPHONIC ACID MIXTURES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-05-13 | — | — | WO | disclosed |
| WO-1993009242-A1 | ENZYMATIC PREPARATION OF N-(PHOSPHONOMETHYL)GLYCINE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-05-13 | — | — | WO | disclosed |