Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OR51E2 | Q9H255 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.35 |
| ▸ | LDHA | P00338 | 1/20 | 0.35 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.35 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.35 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.35 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.33 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.33 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycolic Acid SCHEMBL28620464 | 0.97 | OR51E2 (0.35) | OR51E2ALDH1A1ALOX15CYP2D6TSHR | |
| Oxalic Acid SCHEMBL16909948 | 0.94 | OR51E2 (0.40) | OR51E2ALDH1A1ALOX15CYP2D6TSHR | |
| Oxalic Acid SCHEMBL9438470 | 0.88 | OR51E2 (0.36) | OR51E2ALDH1A1ALOX15CYP2D6TSHR | |
| Dihydroxyacetone SCHEMBL15173203 | 0.83 | OR51E2 (0.35) | OR51E2TSHRLMNAEGLN1TP53 | |
| Glycolic Acid SCHEMBL9764167 | 0.81 | — | — | |
| Glyoxylate SCHEMBL16817729 | 0.81 | — | — | |
| Glyoxylate SCHEMBL17768417 | 0.81 | — | — | |
| Glycolic Acid SCHEMBL811403 | 0.80 | LMNA (0.50) | OR51E2ALDH1A1ALOX15CYP2D6TSHR | |
| Glycolic Acid SCHEMBL1222 | 0.80 | — | — | |
| Glycolic Acid SCHEMBL1331333 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900847-B1 | ELETROCHEMICAL REDUCTION OF CO2 WITH CO-OXIDATION OF AN ALCOHOL | AVANTIUM KNOWLEDGE CENTRE BV (NL) | 2021-03-24 | — | — | EP | claimed |
| EP-2900847-A2 | ELETROCHEMICAL REDUCTION OF CO2 WITH CO-OXIDATION OF AN ALCOHOL | Liquid Light, Inc. (US) | 2015-08-05 | — | — | EP | claimed |
| US-20140367274-A1 | Electrochemical Reduction of CO2 with Co-Oxidation of an Alcohol | AVANTIUM KNOWLEDGE CENTRE B.V. (NL) | 2014-12-18 | — | — | US | claimed |
| WO-2014046798-A2 | ELECTROCHEMICAL REDUCTION OF CO2 WITH CO-OXIDATION OF AN ALCOHOL | LIQUID LIGHT, INC. (US) | 2014-03-27 | — | — | WO | claimed |
| US-20130140187-A1 | Electrochemical Reduction of CO2 with Co-Oxidation of an Alcohol | LIQUID LIGHT, INC. (US) | 2013-06-06 | — | — | US | claimed |
| EP-1997129-A2 | LOW PH POST-CMP RESIDUE REMOVAL COMPOSITION AND METHOD OF USE | ADVANCED TECHNOLOGY MATERIALS, INC. (US) | 2008-12-03 | — | — | EP | claimed |
| WO-2007092800-A2 | LOW PH POST-CMP RESIDUE REMOVAL COMPOSITION AND METHOD OF USE | ADVANCED TECHNOLOGY MATERIALS, INC. (US) | 2007-08-16 | — | — | WO | claimed |
| US-20200261419-A1 | COMBINATIONS FOR THE TREATMENT OF KIDNEY STONES | WAKE FOREST UNIVERSITY HEALTH SCIENCES (US) | 2020-08-20 | — | — | US | disclosed |
| US-20200262794-A1 | GLYCOLATE OXIDASE INHIBITORS AND METHODS OF USE FOR THE TREATMENT OF KIDNEY STONES | UAB RESEARCH FOUNDATION | 2020-08-20 | — | — | US | disclosed |
| EP-3386949-A1 | GLYCOLATE OXIDASE INHIBITORS AND METHODS OF USE FOR THE TREATMENT OF KIDNEY STONES | Wake Forest University Health Sciences (US) | 2018-10-17 | — | — | EP | disclosed |
| EP-3313994-A1 | CARBON-NEUTRAL AND CARBON-POSITIVE PHOTORESPIRATION BYPASS ROUTES SUPPORTING HIGHER PHOTOSYNTHETIC RATE AND YIELD | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2018-05-02 | — | — | EP | disclosed |
| WO-2017100266-A1 | GLYCOLATE OXIDASE INHIBITORS AND METHODS OF USE FOR THE TREATMENT OF KIDNEY STONES | WAKE FOREST UNIVERSITY HEALTH SCIENCES (US) | 2017-06-15 | — | — | WO | disclosed |
| WO-2016207219-A1 | CARBON-NEUTRAL AND CARBON-POSITIVE PHOTORESPIRATION BYPASS ROUTES SUPPORTING HIGHER PHOTOSYNTHETIC RATE AND YIELD | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2016-12-29 | — | — | WO | disclosed |
| CN-101044246-A | Methods and kits for assaying myeloperoxidase by means of enzymatic glycolate-glyoxylate cycling reactions | GEN ATOMICS (US) | 2007-09-26 | — | — | CN | disclosed |
| CN-101044246-A | Methods and kits for assaying myeloperoxidase by means of enzymatic glycolate-glyoxylate cycling reactions | GEN ATOMICS (US) | 2007-09-26 | — | — | CN | disclosed |
| EP-1776466-A1 | METHODS AND KITS FOR ASSAYING MYELOPEROXIDASE BY MEANS OF ENZYMATIC GLYCOLATE-GLYOXYLATE CYCLING REACTIONS | GENERAL ATOMICS (US) | 2007-04-25 | — | — | EP | disclosed |
| WO-2007038524-A2 | COCRYSTALLIZATION METHODS | SSCI, INC. (US) | 2007-04-05 | — | — | WO | disclosed |
| WO-2006020762-A1 | METHODS AND KITS FOR ASSAYING MYELOPEROXIDASE BY MEANS OF ENZYMATIC GLYCOLATE-GLYOXYLATE CYCLING REACTIONS | GENERAL ATOMICS (US) | 2006-02-23 | — | — | WO | disclosed |
| US-5187307-A | Adding methylene chloride to reactants | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200261419-A1 | COMBINATIONS FOR THE TREATMENT OF KIDNEY STONES | XDH, GRHPR, GLS | OR51E2 4380/4885ALDH1A1 335/4885ALOX15 290/4885 |
| US-20200262794-A1 | GLYCOLATE OXIDASE INHIBITORS AND METHODS OF USE FOR THE TREATMENT OF KIDNEY STONES | XDH, PNPO, LOX | OR51E2 3832/4885ALDH1A1 567/4885ALOX15 95/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.