SCHEMBL9438522

SCHEMBL9438522

CCC1(c2ccc3ccccc3c2)CO1

nearest known ligand 0.44

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 13/20 0.44
SLC6A3 Q01959 13/20 0.44
UTS2R Q9UKP6 2/20 0.44
SLC6A2 P23975 8/20 0.44
KCNH2 Q12809 2/20 0.42
CYP1A2 P05177 1/20 0.41
CYP2A6 P11509 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19502719 0.82 UTS2R (0.44) SLC6A4SLC6A3UTS2RSLC6A2
SCHEMBL9370663 0.78 ALOX5 (0.66)
SCHEMBL6493726 0.77 MEN1 (0.40) SLC6A3SLC6A2CYP1A2
SCHEMBL6493723 0.77 MEN1 (0.40) SLC6A3SLC6A2CYP1A2
SCHEMBL10300805 0.76 SLC6A4 (0.45) SLC6A4SLC6A3SLC6A2KCNH2
SCHEMBL26985761 0.76 SLC6A4 (0.45) SLC6A4SLC6A3SLC6A2KCNH2
SCHEMBL11162306 0.72 SLC6A2 (0.48) SLC6A4SLC6A3UTS2RSLC6A2
SCHEMBL18288021 0.71 SLC6A4 (0.42) SLC6A4SLC6A3SLC6A2KCNH2
SCHEMBL17733690 0.71 ALOX5 (0.34) SLC6A4SLC6A3SLC6A2
SCHEMBL8112721 0.71 CHRNA1 (0.40) SLC6A3SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0596047-A1 LUBRICATING COMPOSITIONS AND CONCENTRATES THE LUBRIZOL CORPORATION (US) 1994-05-11 EP disclosed
WO-1993023505-A1 LUBRICATING COMPOSITIONS AND CONCENTRATES THE LUBRIZOL CORPORATION (US) 1993-11-25 WO disclosed
EP-0535221-A1 LUBRICATING COMPOSITIONS. LUBRIZOL CORP (US) 1993-04-07 EP disclosed
EP-0535217-A1 LUBRICATING COMPOSITIONS. LUBRIZOL CORP (US) 1993-04-07 EP disclosed
WO-1992018589-A1 LUBRICATING COMPOSITIONS THE LUBRIZOL CORPORATION (US) 1992-10-29 WO disclosed
WO-1992018588-A1 LUBRICATING COMPOSITIONS THE LUBRIZOL CORPORATION (US) 1992-10-29 WO disclosed
EP-0375769-A4 LUBRICATING OIL COMPOSITIONS AND CONCENTRATES 1991-10-02 EP disclosed
EP-0389573-A4 LUBRICATING OIL COMPOSITIONS AND CONCENTRATES 1991-09-11 EP disclosed
EP-0379566-A4 LUBRICATING OIL COMPOSITIONS 1990-12-27 EP disclosed
EP-0382806-A4 LUBRICATING OIL COMPOSITIONS AND CONCENTRATES 1990-12-27 EP disclosed
EP-0389573-A1 LUBRICATING OIL COMPOSITIONS AND CONCENTRATES. LUBRIZOL CORP (US) 1990-10-03 EP disclosed
EP-0382806-A1 LUBRICATING OIL COMPOSITIONS AND CONCENTRATES. LUBRIZOL CORP (US) 1990-08-22 EP disclosed
EP-0379566-A1 LUBRICATING OIL COMPOSITIONS. LUBRIZOL CORP (US) 1990-08-01 EP disclosed
EP-0375769-A1 LUBRICATING OIL COMPOSITIONS AND CONCENTRATES. LUBRIZOL CORP (US) 1990-07-04 EP disclosed
WO-1990001532-A1 LUBRICATING OIL COMPOSITIONS AND CONCENTRATES THE LUBRIZOL CORPORATION (US) 1990-02-22 WO disclosed
WO-1990001531-A1 LUBRICATING OIL COMPOSITIONS AND CONCENTRATES THE LUBRIZOL CORPORATION (US) 1990-02-22 WO disclosed
WO-1989012668-A1 LUBRICATING OIL COMPOSITIONS THE LUBRIZOL CORPORATION (US) 1989-12-28 WO disclosed
WO-1989012667-A1 LUBRICATING OIL COMPOSITIONS AND CONCENTRATES THE LUBRIZOL CORPORATION (US) 1989-12-28 WO disclosed