SCHEMBL9439003

SCHEMBL9439003

CCCCCCCCCCCCC(O)C[S+](C)[O-]

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 8/20 0.47
FFAR1 O14842 2/20 0.46
FFAR4 Q5NUL3 1/20 0.46
NFKB1 P19838 1/20 0.44
SPHK1 Q9NYA1 2/20 0.41
PSMD14 O00487 2/20 0.41
PLA2G1B P04054 2/20 0.41
MMP2 P08253 2/20 0.41
ATG4B Q9Y4P1 2/20 0.41
HSP90AA1 P07900 1/20 0.41
RAD52 P43351 1/20 0.41
LMNA P02545 2/20 0.40
CYP2D6 P10635 2/20 0.38
GMNN O75496 1/20 0.38
POLB P06746 1/20 0.38
THPO P40225 1/20 0.38
MTOR P42345 1/20 0.38
BLM P54132 1/20 0.38
KDM4E B2RXH2 1/20 0.38
TP53 P04637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1284163 1.00 GPR84 (0.47) GPR84FFAR1FFAR4NFKB1SPHK1
SCHEMBL474084 1.00 GPR84 (0.47) GPR84FFAR1FFAR4NFKB1SPHK1
SCHEMBL10406707 1.00 GPR84 (0.47) GPR84FFAR1FFAR4NFKB1SPHK1
SCHEMBL7435821 1.00 GPR84 (0.47) GPR84FFAR1FFAR4NFKB1SPHK1
SCHEMBL11504238 1.00 GPR84 (0.47) GPR84FFAR1FFAR4NFKB1SPHK1
SCHEMBL9596574 0.93 GPR84 (0.42) GPR84FFAR1FFAR4NFKB1PSMD14
SCHEMBL11448593 0.91 GPR84 (0.45) GPR84FFAR1FFAR4NFKB1PSMD14
SCHEMBL1495346 0.85 GPR84 (0.53) GPR84FFAR1FFAR4NFKB1SPHK1
SCHEMBL18279506 0.85 GPR84 (0.53) GPR84FFAR1FFAR4NFKB1SPHK1
SCHEMBL10333309 0.85 GPR84 (0.53) GPR84FFAR1FFAR4NFKB1SPHK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0327263-B1 Hair growth stimulation with nitroxide and other radicals PROCTOR PETER H (US) 1994-09-07 EP disclosed
EP-0232311-B1 TOPICAL COMPOSITION AND METHOD FOR STIMULATING HAIR GROWTH PROCTOR, Peter H. (US) 1993-05-12 EP disclosed
EP-0327263-A1 Hair growth stimulation with nitroxide and other radicals PROCTOR, Peter H. (US) 1989-08-09 EP disclosed
EP-0232311-A4 TOPICAL COMPOSITION AND METHOD FOR STIMULATING HAIR GROWTH. PROCTOR PETER H 1988-02-15 EP disclosed
EP-0232311-A1 TOPICAL COMPOSITION AND METHOD FOR STIMULATING HAIR GROWTH. PROCTOR PETER H 1987-08-19 EP disclosed
WO-1987000427-A1 TOPICAL COMPOSITION AND METHOD FOR STIMULATING HAIR GROWTH PROCTOR PETER H 1987-01-29 WO disclosed