SCHEMBL9439006

SCHEMBL9439006

C=CC1(C(=O)c2ccccc2)C=CC=CC1C(=O)O

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CES2 O00748 8/20 0.36
CES1 P23141 7/20 0.36
AKT1 P31749 1/20 0.36
ALDH1A1 P00352 2/20 0.31
LMNA P02545 1/20 0.31
HPGD P15428 1/20 0.31
MAPK1 P28482 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
SRD5A2 P31213 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28212264 0.79
SCHEMBL51519 0.74 NPC1 (0.35) CES2CES1ALDH1A1LMNAMAPK1
SCHEMBL30336215 0.71 AKT1 (0.45) CES2CES1AKT1ALDH1A1LMNA
SCHEMBL7801403 0.71 TSHR (0.36) CES2CES1ALDH1A1LMNAHPGD
SCHEMBL31157635 0.71 NPC1 (0.39) CES2CES1AKT1ALDH1A1HPGD
SCHEMBL11350900 0.70 ALDH1A1 (0.33) CES2CES1ALDH1A1LMNAHPGD
SCHEMBL20448829 0.67
SCHEMBL12230997 0.67
SCHEMBL19032029 0.67 CYP2C19 (0.37) CES2CES1ALDH1A1LMNAMAPK1
SCHEMBL1987457 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0351603-B1 Transvinylation reaction UNION CARBIDE CORP (US) 1994-12-07 EP claimed