Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | PREP | P48147 | 2/20 | 0.48 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CTSL | P07711 | 2/20 | 0.44 |
| ▸ | CTSS | P25774 | 2/20 | 0.44 |
| ▸ | CTSK | P43235 | 2/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9439036 | 1.00 | ACE (0.49) | ACEMEN1KMT2ACYP3A4LMNA | |
| SCHEMBL9439084 | 1.00 | ACE (0.49) | ACEMEN1KMT2ACYP3A4LMNA | |
| SCHEMBL9170195 | 0.87 | ACE (0.64) | ACEMEN1KMT2ACYP3A4LMNA | |
| SCHEMBL9439136 | 0.87 | ACE (0.64) | ACEMEN1KMT2ACYP3A4LMNA | |
| SCHEMBL9170201 | 0.87 | ACE (0.64) | ACEMEN1KMT2ACYP3A4LMNA | |
| SCHEMBL10591582 | 0.87 | ACE (0.64) | ACEMEN1KMT2ACYP3A4LMNA | |
| SCHEMBL23645269 | 0.81 | HTR2C (0.48) | ACEMEN1KMT2APREPALDH1A1 | |
| SCHEMBL9438775 | 0.79 | ACE (0.66) | ACEMEN1KMT2ACYP3A4LMNA | |
| SCHEMBL9438933 | 0.79 | ACE (0.69) | ACEMEN1KMT2ACYP3A4LMNA | |
| SCHEMBL9438765 | 0.79 | ACE (0.66) | ACEMEN1KMT2ACYP3A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5348944-A | Hypotensive agents | SCHERING CORPORATION (US) | 1994-09-20 | — | — | US | disclosed |
| WO-1986007056-A1 | HYPOGLYCEMIC THIAZOLIDINEDIONES | PFIZER INC. (US) | 1986-12-04 | — | — | WO | disclosed |
| EP-0050800-A1 | Carboxyalkyl dipeptides, processes for their production and pharmaceutical compositions containing them | SCHERING CORPORATION (US) | 1982-05-05 | — | — | EP | disclosed |