Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 14/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | CDK4 | P11802 | 3/20 | 0.53 |
| ▸ | CCND1 | P24385 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9439699 | 1.00 | TRPV1 (0.59) | TRPV1ALDH1A1CDK4CCND1TSHR | |
| SCHEMBL9439611 | 0.87 | TRPV1 (0.57) | TRPV1 | |
| SCHEMBL998142 | 0.85 | TRPV1 (0.78) | TRPV1CDK4CCND1 | |
| SCHEMBL9439605 | 0.83 | TRPV1 (0.56) | TRPV1CDK4CCND1 | |
| SCHEMBL996814 | 0.82 | TRPV1 (0.69) | TRPV1ALDH1A1CDK4CCND1 | |
| SCHEMBL9439483 | 0.81 | TRPV1 (0.51) | TRPV1CDK4CCND1 | |
| SCHEMBL1001165 | 0.78 | TRPV1 (0.74) | TRPV1 | |
| SCHEMBL9439297 | 0.77 | UCHL1 (0.61) | TRPV1CDK4CCND1 | |
| SCHEMBL9439306 | 0.77 | UCHL1 (0.61) | TRPV1CDK4CCND1 | |
| SCHEMBL1000695 | 0.76 | TRPV1 (0.61) | TRPV1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5340801-A | Compounds having cholecystokinin and gastrin antagonistic properties | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1994-08-23 | — | — | US | disclosed |