SCHEMBL9439650

SCHEMBL9439650

Cc1ccc(OC2CC(C)CCC2C(C)C)cc1

nearest known ligand 0.53

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.47
LMNA P02545 1/20 0.47
NFE2L2 Q16236 1/20 0.46
HPGD P15428 1/20 0.44
CYP19A1 P11511 2/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
TRPV1 Q8NER1 3/20 0.41
TRPM8 Q7Z2W7 3/20 0.41
P2RX4 Q99571 1/20 0.40
TRPA1 O75762 2/20 0.40
MEN1 O00255 1/20 0.39
NTSR1 P30989 1/20 0.39
KMT2A Q03164 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12760812 0.86 ALDH1A1 (0.46) ALDH1A1LMNANFE2L2HPGDCYP19A1
SCHEMBL10775380 0.86 ALDH1A1 (0.49) ALDH1A1LMNANFE2L2HPGDCYP19A1
SCHEMBL28381197 0.86 ALDH1A1 (0.58) ALDH1A1LMNANFE2L2HPGDCYP19A1
SCHEMBL8984221 0.86 ALDH1A1 (0.58) ALDH1A1LMNANFE2L2HPGDCYP19A1
Phosphine SCHEMBL27943782 0.84 ALDH1A1 (0.57) ALDH1A1LMNANFE2L2HPGDCYP19A1
SCHEMBL8433927 0.84 HRH3 (0.48) ALDH1A1LMNANFE2L2HPGDCYP19A1
SCHEMBL8432421 0.84 HRH3 (0.48) ALDH1A1LMNANFE2L2HPGDCYP19A1
SCHEMBL31680864 0.83 CYP19A1 (0.57) ALDH1A1LMNANFE2L2HPGDCYP19A1
SCHEMBL31499382 0.82 ALDH1A1 (0.43) ALDH1A1LMNANFE2L2HPGDCYP19A1
SCHEMBL28936351 0.82 ALDH1A1 (0.43) ALDH1A1LMNANFE2L2HPGDCYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5292913-A Labeling with deuterium or tritium MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1994-03-08 US disclosed
EP-0262227-B1 PROCESS FOR THE PREPARATION OF MYOINOSITOL DERIVATIVES MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-01-20 EP disclosed
US-4952717-A Myoinositol derivatives and preparation process thereof MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1990-08-28 US disclosed
EP-0262227-A1 Process for the preparation of myoinositol derivatives MITSUI TOATSU CHEMICALS, Inc. (JP) 1988-04-06 EP disclosed