Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | PPARA | Q07869 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9439503 | 0.87 | ALOX5 (0.58) | TMEM97SMN1; SMN2NPSR1ALOX5CYP1A2 | |
| SCHEMBL9439285 | 0.82 | ALOX5 (0.60) | TMEM97SMN1; SMN2NPSR1ALOX5CYP1A2 | |
| SCHEMBL9439551 | 0.81 | ALOX5 (0.54) | TMEM97SMN1; SMN2NPSR1ALOX5CYP1A2 | |
| SCHEMBL8133052 | 0.80 | CYP1A2 (0.65) | TMEM97SMN1; SMN2NPSR1ALOX5CYP1A2 | |
| SCHEMBL9622398 | 0.80 | SMN1; SMN2 (0.71) | TMEM97SMN1; SMN2NPSR1ALOX5CYP1A2 | |
| SCHEMBL30423143 | 0.80 | SMN1; SMN2 (0.71) | TMEM97SMN1; SMN2NPSR1ALOX5CYP1A2 | |
| SCHEMBL9439564 | 0.79 | ALOX5 (0.64) | TMEM97SMN1; SMN2NPSR1ALOX5PPARA | |
| SCHEMBL9388713 | 0.79 | ALOX5 (0.61) | TMEM97SMN1; SMN2NPSR1ALOX5CYP1A2 | |
| SCHEMBL9744120 | 0.79 | ALOX5 (0.55) | TMEM97SMN1; SMN2NPSR1ALOX5CYP1A2 | |
| SCHEMBL11113364 | 0.79 | TMEM97 (0.60) | TMEM97SMN1; SMN2NPSR1ALOX5PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5294629-A | Benzothiazole and benzimidazole derivatives and antiulcer agent containing the same | MEIJI SEIKA KAISHA, LTD. (JP) | 1994-03-15 | — | — | US | disclosed |
| EP-0370436-A2 | Novel benzothiazole and benzimidazole derivatives and antiulcer agent containing the same | MEIJI SEIKA KAISHA LTD. (JP) | 1990-05-30 | — | — | EP | disclosed |